D. Friedman1, L. Lovig2, M. Halushka3, R. Clancy4, P. Izmirly5, J. Buyon6
2017 Vol.35, N°5 - PI 0857, PF 0859
It is currently recommended that hydroxychloroquine (HCQ) be maintained during pregnancy in patients with systemic lupus erythematosus. Recent data suggest that this Toll-like receptor inhibitor may also reduce the recurrence rate of anti-SSA/Ro associated congenital heart block (CHB). This case report describes a unique situation in which a CHB-afflicted, HCQ-exposed pregnancy was electively terminated. The heart did not reveal any characteristic features of cardiotoxicity, providing further evidence supporting the safety of foetal exposure to HCQ.
PMID: 28598777 [PubMed]
Received: 19/12/2016 - Accepted : 28/03/2017 - In Press: 06/06/2017 - Published: 15/09/2017