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Coexistence of Behcet's disease and chronic myelomonocyte leukemia with trisomy 8: a case report and review of the literature

M.G. Mantzourani, K. Chantziara, I. Thanopoulou, H. Variami, G. Vaiopoulos, G.A. Pangalis

First Department of Internal Medicine, University of Athens, Medical School, Laikon General Hospital, Athens, Greece.

CER3620
2009 Vol.27, N°2 ,Suppl.53 - PI 0085, PF 0087
Case Reports

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Rheumatology Article

 

Abstract

Behçet`s disease (BD) is a multisystem inflammatory vasculitis of unknown etiology and pathogenesis. Coexistence of BD along with hematological malignancies is extremely rare. We describe a patient diagnosed with BD and chronic myelomonocytic leukaemia (CMML) with trisomy 8. This case suggests that trisomy 8 may be involved in the concurrent manifestation of myelodysplastic syndrome (MDS) and BD with gastrointestinal ulcers.

PMID: 19796540 [PubMed]