32british

The British version of the Childhood Health Assessment Questionnaire (CHAQ) and the Child Health Questionnaire (CHQ)

J. Nugent¹, N. Ruperto², J. Grainger¹, C. Machado¹, S. Sawhney¹, E. Baildam³, J. Davidson⁴, H. Foster⁵, A. Hall⁶, P. Hollingworth⁷, J. Sills⁴, H. Venning8, J.E. Walsh⁹, J.M. Landgraf¹⁰, M. Roland¹¹, P. Woo¹, K.J. Murray¹, for the Paediatric Rheumatology International Trials Organisation (PRINTO)

¹Institute of Child Health, University College, London, United Kingdom; ²Laboratorio di Informatica Medica, IRCCS S. Matteo, Pavia, Italy; ³Booth Hall Children's Hospital, Manchester; ⁴Royal Liverpool Children's Hospital Alder Hey, Liverpool; ⁵Freeman Hospital Musculoskeletal Unit, Newcastle; ⁶Wexham Park Hospital, Slough; ⁷Southmead Hospital, Bristol; ⁸Queen's Medical Centre, Nottingham; ⁹Yorkhill NHS Trust, Glasgow, United Kingdom; ¹⁰HealthAct, Boston, MA, USA; ¹¹Department of General Practice, University of Manchester, Manchester, United Kingdom.

ABSTRACT
We report herein the results of the cross-cultural adaptation and validation into the British language of the parent's version of two health related quality of life instruments. The Childhood Health Assessment Questionnaire (CHAQ) is a disease specific health instrument that measures functional ability in daily living activities in children with juvenile idiopathic arthritis (JIA). The Child Health Questionnaire (CHQ) is a generic health instrument designed to capture the physical and psychosocial well-being of children independently from the underlying disease. A total of 440 subjects were enrolled: 219 patients with JIA (17% systemic onset, 41% polyarticular onset, 33% extended oligoarticular subtype, and 9% persistent oligoarticular subtype) and 221 healthy children. The CHAQ clinically discriminated between healthy subjects and JIA patients, with the systemic, polyarticular and extended oligoarticular subtypes having a higher degree of disability, pain, and a lower overall well-being when compared to their healthy peers. Also the CHQ clinically discriminated between healthy subjects and JIA patients, with the systemic onset, polyarticular onset and extended oligoarticular subtypes having a lower physical and psychosocial well-being when compared to their healthy peers.
In conclusion the British version of the CHAQ-CHQ is a reliable, and valid tool for the functional, physical and psychosocial assessment of children with JIA.

Key words
British Childhood Health Assessment Questionnaire (CHAQ), British Child Health Questionnaire (CHQ), cross cultural adaptation and psychometric evaluation, health related quality of life, juvenile idiopathic arthritis (JIA), healthy children.

Supported by a grant from the European Union (BMH4-983531 CA), by IRCCS Policlinico S. Matteo (Pavia, Italy), and by Telecom Italy, and by a grant from the Arthritis Research Campaign, United Kingdom.

Please address correspondence and requests for reprints to either: Kevin Murray, MBBS, FRACP, Great Ormond St Hospital for Sick Children, Rheumatology Unit, London WCIN 3JH, UK
E-mail: kevin.murray@gosh-tr.nthames.nhs.uk
or PRINTO, IRCCS Policlinico S. Matteo, Pediatria Generale e Reumatologia, Piazzale Golgi, 2, 27100 Pavia, Italy.
E-mail: nruperto@smatteo.pv.it
WWW: http://www.medit.it/printo/