Periarticular corticosteroid treatment of the
sacroiliac joint in patients with seronegative spondylarthropathy
R. Luukkainen1, M. Nissilä2, E. Asikainen1, M. Sanila1,
K. Lehtinen2, A. Alanaatu1, H. Kautiainen2
1Satalinna Hospital, Harjavalta and 2Rheumatism Foundation Hospital,
Heinola, Finland
ABSTRACT
Objective
To evaluate the efficacy of periarticular corticosteroid injection of the sacroiliac joint
(SIJ) in patients with seronegative spondylarthropathy in a double blind, controlled
study.
Methods
20 patients with seronegative spondylarthropathy and clinical sacroiliitis entered the
study. In 10 patients one affected SIJ was treated with periarticular injection of 1.5 ml
(40 mg/ml) methylprednisoloneacetate and 1.5 ml (20 mg/ml) lignocaine (MP group), whereas
10 patients received 1.5 ml isotonic sodium chloride and 1.5 ml (20 mg/ml) lignocaine
(non-MP group). Clinical assessment at the onset of the study and after two months
follow-up included the patients' estimation of pain in the SIJ by the visual analogue
scale (VAS) and by a pain index which was calculated from tenderness and stressing tests
on the SIJ.
Results
At the two months follow-up examination the VAS (p = 0.02) and the pain index (p = 0.01)
had improved significantly in the MP group compared with the non-MP group.
Conclusion
The results of our study indicate that the periarticular injection of methylprednisolone
may be effective in the treatment of clinical sacroiliitis in patients with seronegative
spondylarthropathy.
Key words
periarticular, corticosteroids, spondylarthropathy, sacroiliac joint.
Please address correspondence and reprint
requests to: Reijo Luukkainen, MD, Kreetalankatu 5 C, 29200 Harjavalta, Finland.
Received on May 22, 1997; accepted in revised form on August 10, 1998.
Clin Exp Rheumatol 1999; 17: 88-90.
© Copyright Clinical and Experimental
Rheumatology 1999.