Hepatotoxicity of parenteral gold therapy in rheumatoid arthritis: A case report and review of the literature

P.A.W. te Boekhorst, P. Barrera, R.F.J.M. Laan, L.B.A. van de Putte

Department of Rheumatology, University Hospital Nijmegen, Nijmegen, The Netherlands

ABSTRACT
We report a case of severe hepatotoxic reaction during gold therapy for rheumatoid arthritis. The previous literature on this condition is reviewed and the possible mechanisms of gold-induced hepatotoxicity are discussed.

Key words
Rheumatoid arthritis (RA), hepatoxicity, gold therapy.

Please address correspondence and reprint requests to: Pilar Barrera, MD, PhD, Department of Rheumatology, University Hospital Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

Clin Exp Rheumatol 1999; 17: 359-62.
© Copyright Clinical and Experimental Rheumatology 1999.