Lymphoproliferative disorders in paediatric rheumatic diseases. A report of two cases

R. Merino¹, J. de Inocencio³, P. García-Miguel², J. García-Consuegra¹

¹Paediatric Rheumatology Unit and ²Oncology Unit, University Hospital La Paz, Madrid; ³CS Estrecho de Corea, Instituto Madrileño de la Salud Area 4, Madrid, Spain.

ABSTRACT
Lymphoproliferative disorders (LPD) are reported with a much lower frequency in children with rheumatic diseases than in their adult counterparts. We describe 2 patients who developed a lymphoma during the course of the disease. The first is a 16-year-old girl diagnosed with systemic juvenile idiopathic arthritis 6 years before who developed a mucosa-associated lymphoid tissue (MALT) lymphoma. The second report involves a boy diagnosed with systemic lupus erythematosus at 9 years of age who developed a Hodgkin's lymphoma 9 years after the disease onset. In spite of the low frequency of LPD in children with rheumatic diseases, these processes do occur.

Please address correspondence to: Dr Rosa Merino, Unidad de Reumatología Pediátrica, Hospital Universitario La Paz, Paseo de la Castellana 261, 20046 Madrid, Spain. 
E-mail: reumaped.hulp@salud.madrid.org

Clin Exp Rheumatol 2004; 22: 649-650.
© Copyright Clinical and Experimental Rheumatology 2004.