ab226014

Neurological manifestations of anti-phospholipid (Hughes) syndrome

M.C. Antunes^1,2, D. D'Cruz¹, G.R.V. Hughes¹

The Lupus Research Unit, The Rayne Institute, St Thomas' Hospital, London, UK; ²Internal Medicine Department, Curry Cabral's Hospital, Lisbon, Portugal.

ABSTRACT
In the 21 years since the description of the antiphospholipid syndrome (APS), neurological features have become recognised as some of the most important and common aspects of the syndrome. Recognition of the relationship between APS and central nervous system impairment could open the door to improved treatment and outcomes in some neurological syndromes.

Key words
Antiphospholipid syndrome, anticardiolipin antibodies, lupus anticoagulant, hypercoagulability, thrombosis.

Please address correspondence to: Dr. G.R.V. Hughes, The Lupus Research Unit, The Rayne Institute, Lambeth Wing, St Thomas' Hospital, London SE1 EH, UK.
E-mail: graham.hughes@kcl.ac.uk