Musculoskeletal manifestations of psoriatic arthritis
The joint in psoriatic arthritis
M. Mortezavi1, R. Thiele2, C. Ritchlin3
- Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, USA. mahta_mortezavi@urmc.rochester.edu
- Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, USA.
- Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, USA.
CER9008
2015 Vol.33, N°5 ,Suppl.93
PI 0020, PF 0025
Musculoskeletal manifestations of psoriatic arthritis
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PMID: 26472472 [PubMed]
Received: 28/09/2015
Accepted : 28/09/2015
In Press: 15/10/2015
Published: 16/10/2015
Abstract
Psoriatic arthritis (PsA), a chronic inflammatory joint disease associated with psoriasis, is notable for diversity in disease presentation, course and response to treatment. Equally varied are the types of musculoskeletal involvement which include peripheral and axial joint disease, dactylitis and enthesitis. In this review, we focus on the psoriatic joint and discuss pathways that underlie synovial, cartilage and bone inflammation and highlight key histopathologic features. The pivotal inflammatory mechanisms and pathobiology of PsA parallel findings in other forms of spondyloarthritis but are distinct from disease pathways described in rheumatoid synovitis and bone disease. The diagnosis of PsA from both a clinical and imaging perspective is also discussed.
