Diagnosis
Validity of the Workers Productivity and Activity Impairment Questionnaire: Specific Health Problem (WPAI:SHP) in patients with systemic sclerosis
K. Morrisroe1, W. Stevens2, M. Huq3, J. Sahhar4, G.-S. Ngian5, J. Zochling6, J. Roddy7, S.M. Proudman8, M. Nikpour9
- Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; and Department of Rheumatology, St. Vincent’s Hospital, Melbourne, Australia.
- Department of Rheumatology, St. Vincent’s Hospital, Melbourne, Australia.
- Department of Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Australia.
- Monash University and Monash Health, Clayton, Australia.
- Monash University and Monash Health, Clayton, Australia.
- Department of Rheumatology, Menzies Institute for Medical Research, Hobart, Australia.
- Department of Rheumatology, Royal Perth Hospital, Perth, Australia.
- Rheumatology Unit, Royal Adelaide Hospital, North Terrace; and Discipline of Medicine, University of Adelaide, Australia.
- Department of Medicine, The University of Melbourne at St. Vincent’s Hospital; and Department of Rheumatology, St. Vincent’s Hospital, Melbourne, Australia. m.nikpour@unimelb.edu.au
the Australian Scleroderma Interest Group (ASIG)
CER10311
2017 Vol.35, N°4 ,Suppl.106
PI 0130, PF 0137
Diagnosis
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PMID: 28516877 [PubMed]
Received: 09/02/2017
Accepted : 24/04/2017
In Press: 08/05/2017
Published: 12/10/2017
Abstract
OBJECTIVES:
To evaluate the construct validity of the Workers Productivity and Impairment Activity Index: Specific Health Problem (WPAI:SHP) in Australian systemic sclerosis (SSc) patients.
METHODS:
SSc patients, identified through the Australian Scleroderma Cohort Study database, completed the WPAI:SHP and a quality of life instrument (PROMIS-29) cross-sectionally. The construct validity of the WPAI:SHP was assessed by the correlations between the WPAI:SHP and a range of SSc health states. Non-parametric correlation, including Spearman’s correlation (ρ), was used to test the validity of WPAI:SHP and ability to distinguish between different health states.
RESULTS:
A total of 476 completed questionnaires was returned, equating to a response rate of 63.7%. Among those under 65 years of age, 155 patients (55.2%) were in paid employment. Employed patients had a mean (± SD) age of 56.5 (9.8) years and were predominantly female (87.3%) with limited disease subtype (75.6%). The WPAI:SHP showed construct validity based on moderate to strong correlations with health status as assessed by a range of health outcome measures including disease activity (ρ=0.34-0.39, p=0.001), physical function (ρ=0.55-0.62, p=0.001), disease severity(ρ=0.55-0.62, p=0.001), fatigue (ρ= 0.62-0.63, p=0.001), pain (ρ=0.68-0.71, p=0.001), and breathlessness (ρ=0.39-0.46, p=0.001). Furthermore, according to the effect size, the WPAI:SHP scores have a large discriminative ability (d=1.26-1.47) for distinguishing SSc patients with different health outcomes.
CONCLUSIONS:
The WPAI is a valid questionnaire for assessing impairments in paid employment and social activities in SSc patients, and for measuring the relative differences between SSc patients with varying health states.