Full Papers
Childhood adversities in patients with fibromyalgia: are they related to comorbid lifetime major depression?
A. Alciati1, F. Atzeni2, M. Grassi3, D. Caldirola4, A. Riva5, P. Sarzi-Puttini6, G. Perna7
- Department of Clinical Neurosciences, Villa San Benedetto Menni, Hermanas Hospitalarias, FoRiPsi, Albese con Cassano, Como, Italy. alessandra.alciati@gmail.com
- IRCCS Galeazzi Orthopaedic Institute, Milan, Italy.
- Department of Clinical Neurosciences, Villa San Benedetto Menni, Hermanas Hospitalarias, FoRiPsi, Albese con Cassano, Como, Italy.
- Department of Clinical Neurosciences, Villa San Benedetto Menni, Hermanas Hospitalarias, FoRiPsi, Albese con Cassano, Como, Italy.
- Department of Clinical Neurosciences, Villa San Benedetto Menni, Hermanas Hospitalarias, FoRiPsi, Albese con Cassano, Como, Italy.
- Rheumatology Unit, ASST-Fatebenefratelli- L. Sacco University Hospital, Milan, Italy.
- Clinical Neurosciences, Villa S.Benedetto Menni, Hermanas Hospitalarias, Como, Italy; Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Univ. of Maastricht, Netherland; and Psychiatry & Behavioral Sciences, Univ.of Miami, USA.
CER10562
2017 Vol.35, N°3 ,Suppl.105
PI 0112, PF 0118
Full Papers
Free to view
(click on article PDF icon to read the article)
PMID: 28681713 [PubMed]
Received: 08/05/2017
Accepted : 14/05/2017
In Press: 29/06/2017
Published: 29/06/2017
Abstract
OBJECTIVES:
Fibromyalgia (FM) is a syndrome of unknown aetiology that is frequently associated with depressive disorders, and childhood adversities (including maltreatment and parental loss) are frequently described in subjects with FM and depression. The aim of this study was to investigate the extent to which the high percentage of childhood adversities reported by patients with FM is related to FM itself or to a comorbid lifetime depressive disorder.
METHODS:
Ninety-four consecutive FM patients were assessed for lifetime major depression using the DSM-IVSCID-CV interview. Childhood maltreatment was investigated using the Childhood Trauma Questionnaire, and information relating to parental death or separation before the age of 18 years was collected by means of a semi-structured interview. The Zung Self-Rating Depression Scale, used as a quantitative measure of depressive symptoms, and the childhood adversity assessment were recorded at the same time.
RESULTS:
Sixty of the 94 FM patients (63.8%) were diagnosed as having a lifetime major depressive disorder. There were no significant associations between childhood parental loss, the presence/level of maltreatment, the occurrence of a lifetime major depression episode, and the Zung Self-Rating Depression Scale scores.
CONCLUSIONS:
The results of this study suggest that there is no association between childhood adversities and comorbid lifetime major depression in patients with FM. As it would be helpful to prevent the development of FM because of the high cost and limited efficacy of therapeutic interventions, childhood adversities may offer targets for primary prevention.
