One year in review
One year in review 2017: systemic lupus erythematosus
G.M.C. La Paglia1, M.C. Leone2, G. Lepri3, R. Vagelli4, E. Valentini5, A. Alunno6, C. Tani7
- Rheumatology Unit, Department of Medicine, University of Perugia, Italy. lapaglia.giuliana@gmail.com
- Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
- Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Florence, AOUC, Florence, Italy.
- Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
- Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
- Rheumatology Unit, Department of Medicine, University of Perugia, Italy.
- Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
CER10631
2017 Vol.35, N°4
PI 0551, PF 0561
One year in review
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PMID: 28721860 [PubMed]
Received: 21/06/2017
Accepted : 27/06/2017
In Press: 11/07/2017
Published: 13/07/2017
Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that predominately affects women. It is characterised by a broad spectrum of clinical manifestations, however, its course and organ involvement are unpredictable. Although over the last few decades an improvement in survival for SLE patients has been observed, pathogenic mechanisms underlying this disease are still unclear. Comorbidities, due to both disease and treatment, as well as multiple aspects of SLE, are under intensive investigation. Following the previous annual reviews of this series, we hereby provide a critical digest of the recent papers on SLE focusing on pathogenesis, clinical and laboratory features, as well as current and new therapeutic strategies published over the last year.
