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Prevalence and characteristics associated with dactylitis in patients with early spondyloarthritis: results from the ESPeranza cohort

1, 2, 3, 4, 5, 6

 

  1. Rheumatology Department, Hospital Vega Baja, Orihuela, Alicante, Spain.
  2. Rheumatology Department, Hospital Universitario La Paz, IdiPaz, Madrid, Spain.
  3. Rheumatology Department, Hospital de Mérida, Mérida, Badajoz, Spain.
  4. Rheumatology Department, Clínica Universitaria Hospital Virgen de la Arrixaca, Murcia, Spain.
  5. Rheumatology Department, Hospital Universitario Reina Sofía, Cordoba, Spain.
  6. Rheumatology Department, Hospital Universitario La Paz, IdiPaz, Madrid, Spain. eugenio.demiguel@gmail.com

on behalf of the ESPERANZA Group.

CER10932
2018 Vol.36, N°5
PI 0879, PF 0883
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PMID: 29745883 [PubMed]

Received: 01/11/2017
Accepted : 26/02/2018
In Press: 08/05/2018
Published: 26/09/2018

Abstract

OBJECTIVES:
Dactylitis is a typical feature of psoriatic arthritis. However, dactylitis was included as a spondyloarthritis (SpA) feature for both (axial and peripheral) of the ASAS classification criteria, but data about its prevalence are scarce, especially in patients with a recent onset of the disease. Our objective was to determine the prevalence and characteristics associated with dactylitis in patients with early SpA.
METHODS:
A baseline dataset from the ESPeranza cohort was used. This programme included patients who were suspected of having SpA (age <45 years, symptoms duration of 3–24 months and with inflammatory back pain, or asymmetrical arthritis, or spinal/joint pain plus ≥1 of the SpA features). For this study, 609 patients who were diagnosed with SpA by their physician were included. Descriptive, univariable and multivariable logistic regression analyses were employed to investigate the association between the presence of dactylitis and the characteristics associated with SpA.
RESULTS:
Fifty-eight (9.5%) patients currently or previously had dactylitis. In the multivariable analysis, dactylitis was independently associated with peripheral arthritis (OR= 4.83; p<0.001), enthesitis (OR= 2.49; p=0.01), psoriasis (OR= 3.62; p<0.01) and the physician’s visual analogue scale (OR= 0.82; p=0.01). However, 67% of the patients who had dactylitis did not have peripheral arthritis or psoriasis and 15% had predominantly axial disease.
CONCLUSIONS:
Dactylitis is a frequent manifestation in patients with SpA, even during the early stages of the disease. Its presence is mainly associated with peripheral manifestations and psoriasis. Nevertheless, dactylitis is not exclusive of patients with PsA or peripheral manifestations.

Rheumatology Article