One year in review
One year in review 2018: Sjögren’s syndrome
O.D. Argyropoulou1, E. Valentini2, F. Ferro3, M.C. Leone4, G. Cafaro5, E. Bartoloni6, C. Baldini7
- Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Greece.
- Rheumatology Unit, University of Perugia, Italy.
- Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
- Rheumatology Unit, University of Perugia, Italy.
- Rheumatology Unit, University of Perugia, Italy.
- Rheumatology Unit, University of Perugia, Italy. elena.bartolonibocci@unipg.it
- Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
CER11493
2018 Vol.36, N°3 ,Suppl.112
PI 0014, PF 0026
One year in review
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PMID: 30156536 [PubMed]
Received: 03/07/2018
Accepted : 03/07/2018
In Press: 18/07/2018
Published: 12/08/2018
Abstract
Sjögren’s syndrome is a complex and potentially disabling slow progressive, systemic disorder. During the last twelve months several original and important contributions have been published on the pathogenesis, diagnosis and therapy of the disease. This review, following the others of this series is aimed at summarising some of the most significant studies that have been recently published. Regarding the pathogenesis, we will specifically focus on novel insights on miRNA, gut microbiota, adaptive and innate autoimmunity and animal models. Concerning novelties in pSS diagnosis, we will focus on salivary gland ultrasonography and histology. Finally, we will conclude with an update of the clinical manifestations of the disease and with an overview of the future therapies.
