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Disease modification in osteoarthritis: are we there yet?


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  1. Rheumatology Department, Royal North Shore Hospital and Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Australia.
  2. Rheumatology Department, Royal North Shore Hospital and Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Australia. david.hunter@sydney.edu.au

CER12727
2019 Vol.37, N°5 ,Suppl.120
PI 0135, PF 0140
Specific organs

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PMID: 31621568 [PubMed]

Received: 02/09/2019
Accepted : 04/09/2019
In Press: 15/10/2019
Published: 15/10/2019

Abstract

A disease-modifying osteoarthritis drug (DMOAD) is a drug that modifies the underlying OA pathophysiology and potentially inhibits the structural damage to prevent or reduce long-term disability with potential symptomatic relief. The focus of this narrative review is on describing the state of the field for disease-modifying pharmacologic agents that are in late-stage development-specifically phase 2/3.

Rheumatology Article