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One year in review

 

One year in review 2020: gout


1, 2, 3, 4, 5, 6, 7

 

  1. Centre for Gout and Metabolic Bone and Joint Diseases, SS. Giovanni e Paolo Hospital, Venezia, ltaly. punzileonardo@gmail.com
  2. Rheumatology Unit, Department of Medicine - DIMED, University of Padova, ltaly.
  3. Rheumatology Unit, Department of Medicine - DIMED, University of Padova, ltaly.
  4. Department of Surgery, Oncology and Gastroenterology - DISCOG, University of Padova, ltaly.
  5. Clinical Nutrition Unit, Department of Medicine - DIMED, University of Padova, ltaly.
  6. Rheumatology, Department of Clinical Sciences, University of Ferrara, and Epidemiology Unit, Italian Society for Rheumatology, Milano, Italy.
  7. Rheumatology Unit, Department of Medicine - DIMED, University of Padova, ltaly.

CER14022
2020 Vol.38, N°5
PI 0807, PF 0821
One year in review

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PMID: 33034561 [PubMed]

Received: 09/09/2020
Accepted : 18/09/2020
In Press: 02/10/2020
Published: 02/10/2020

Abstract

Gout is the most prevalent form of inflammatory arthritis, with a strong impact on individual health and healthcare systems. This article reviews clinical and experimental evidences about gout emerged throughout the 2019. Starting with an epidemiological analysis, the review explores new insights on genetic factors influencing the development of gout flare, pathogenetic mechanisms, risk factors for the disease and comorbidities. An overview on pharmacological therapies and recent knowledge on the impact of lifestyle and dietary habits are also included. Finally, the review contains a novel section on animal models, which reflects the renewed interest of researchers in the acute process triggered by monosodium urate crystals.

Rheumatology Article