impact factor
logo
 

Clinical aspects

 

Work productivity and activity impairment in patients with primary Sjögren's syndrome


1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22

 

  1. Catalán Pellet Medical Offices, Buenos Aires, Argentina. vanesa_bejarano@hotmail.com
  2. Catalán Pellet Medical Offices, Buenos Aires, Argentina.
  3. Catalán Pellet Medical Offices, Buenos Aires, Argentina.
  4. Catalán Pellet Medical Offices, Buenos Aires, Argentina.
  5. Catalán Pellet Medical Offices, Buenos Aires, Argentina.
  6. Tornú Hospital, Buenos Aires, Argentina.
  7. German Hospital of Buenos Aires, Argentina.
  8. German Hospital of Buenos Aires, Argentina.
  9. German Hospital of Buenos Aires, Argentina.
  10. Private Hospital of Córdoba, Argentina.
  11. Private Hospital of Córdoba, Argentina.
  12. Córdoba Hospital, Argentina.
  13. Córdoba Hospital, Argentina.
  14. British Hospital of Buenos Aires, Argentina.
  15. San Martín de La Plata Hospital, Argentina.
  16. San Martín de La Plata Hospital, Argentina.
  17. Italian Hospital of Buenos Aires, Argentina.
  18. Italian Hospital of Buenos Aires, Argentina.
  19. Bessone Clinic, Buenos Aires, Argentina.
  20. IPRI, Santiago del Estero, Argentina.
  21. CEMIC, Caba, Argentina.
  22. Catalán Pellet Medical Offices, Buenos Aires, Argentina.

CER14894
2021 Vol.39, N°6 ,Suppl.133
PI 0093, PF 0099
Clinical aspects

Free to view
(click on article PDF icon to read the article)

PMID: 34796845 [PubMed]

Received: 14/06/2021
Accepted : 13/09/2021
In Press: 10/11/2021
Published: 15/12/2021

Abstract

OBJECTIVES:
In this observational, analytical, cross-sectional study we aimed to describe the impact of primary Sjögren’s syndrome (pSS) on work productivity and activities of daily living (ADL) to assess the association between ADL impairment and clinical manifestations and to compare ADL impairment according to patients’ socioeconomic condition.
METHODS:
Patients diagnosed with pSS attending 11 centres from Argentina were included. To evaluate work productivity and ADL impairment, a work productivity and activity impairment questionnaire (WPAI) was used. A multiple linear regression model was performed, considering deterioration on ADL due to health as a dependent variable, adjusted for potential confounders.
RESULTS:
252 patients were included, 98.4% were women, with a mean age of 52.6 years (±14.8). The average percentage of time lost due to health was 15.7 hours (±30.1 95% CI: 9.6–21.9); the decrease in work productivity was 27.2 (±30.2 95% CI: 21.3–33.1), the total disability was 33.7 (±35.8 95% CI: 26.4–4) and ADL deterioration was 34.2 (±30.9. 95% CI: 30.4–38). In the multivariate analysis, xerostomia, arthritis and depression showed significant and independent association. The mean of ADL impairment was 38.2 (±30.7) in patients attending public centres versus 28 (± 30.6) in private centres, which was a statistically significant difference.
CONCLUSIONS:
We found a compromise in all WPAI domains. Arthritis, xerostomia and depression were associated significantly and independently with ADL impairment. Deterioration in ADL was greater in patients treated in public centres. Considering these aspects will allow a better understanding of patients who suffer from this disease.

DOI: https://doi.org/10.55563/clinexprheumatol/6rd9mr

Rheumatology Article