Case Reports
Hoarseness as the presentation of immunoglobulin G4-related disease with vocal cord and mediastinal infiltration
E. Dourado1, A.S. Martins2, J.E. Fonseca3
- Rheumatology Department, Centro Hospitalar Universitário Lisboa Norte (CHULN), Centro Académico de Medicina de Lisboa (CAML), ERN ReCONNET Full Member, and Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, CAML, Lisbon, Portugal. 25546@chln.min-saude.pt
- Department of Haematology and Bone Marrow Transplantation, CHULN, CAML, Lisbon, Portugal.
- Rheumatology Department, Centro Hospitalar Universitário Lisboa Norte (CHULN), Centro Académico de Medicina de Lisboa (CAML), ERN ReCONNET Full Member, and Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, CAML, Lisbon, Portugal.
CER15049
2022 Vol.40, N°5 ,Suppl.134
PI 0113, PF 0115
Case Reports
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PMID: 35238752 [PubMed]
Received: 31/07/2021
Accepted : 22/02/2022
In Press: 01/03/2022
Published: 18/05/2022
Abstract
Immunoglobulin G4-related disease is a rare fibroinflammatory infiltrative condition with heterogeneous clinical manifestations. We present the case of a 64-year-old man that presented with hoarseness due to vocal cord involvement, a particularly rare manifestation. A large mediastinal mass compressing thoracic large vessels was also identified. The patient was initially treated with glucocorticoids but had relapses during glucocorticoid tapering. Rituximab was started after a careful pre-treatment evaluation of the infectious risk and treatment of comorbidities.
