Reviews
Current concepts and advances in dermatomyositis: a dermatological perspective
D. Lim1, D. Fiorentino2, V. Werth3
- Dermatology, Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center, Philadelphia, and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
- Department of Dermatology, Stanford University School of Medicine, Redwood City, CA, USA.
- Dermatology, Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center, Philadelphia, and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. werth@pennmedicine.upenn.edu
CER16382
2023 Vol.41, N°2
PI 0359, PF 0369
Reviews
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PMID: 36622138 [PubMed]
Received: 19/11/2022
Accepted : 30/11/2022
In Press: 03/01/2023
Published: 01/03/2023
Abstract
Dermatomyositis (DM) is an autoimmune disorder in which clinically amyopathic DM, characterised by hallmark cutaneous findings in the absence of clinical weakness, represents 20% of patients. This review will highlight current concepts and recent advances made in DM from a dermatological perspective, with a discussion of skin-predominant DM and its distinct challenges regarding diagnosis and management as well as their implications in clinical trials. An update will be presented with respect to classification criteria, pathogenesis in cutaneous DM, myositis-specific autoantibodies and their associations with cutaneous findings, skin-specific outcome measures and new therapeutics with their efficacy in skin disease.
