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One year in review

 

Systemic vasculitis: one year in review 2023

1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13

 

  1. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
  2. Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital Santa Maria della Misericordia, Udine, Italy.
  3. Department of Rheumatology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
  4. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
  5. Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital Santa Maria della Misericordia, Udine, Italy.
  6. Department of Rheumatology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
  7. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
  8. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
  9. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
  10. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
  11. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
  12. Clinic of Rheumatology, Department of Medical and Biological Sciences, University Hospital Santa Maria della Misericordia, Udine, Italy.
  13. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy. chiara.baldini74@gmail.com

CER16747
2023 Vol.41, N°4
PI 0765, PF 0773
One year in review

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PMID: 37073639 [PubMed]

Received: 10/04/2023
Accepted : 13/04/2023
In Press: 18/04/2023
Published: 18/04/2023

Abstract

Systemic vasculitides are heterogeneous disabling diseases characterised by chronic inflammation of the blood vessels potentially leading to tissue destruction and organ failure. The recent COVID-19 pandemic has had a significant impact on the epidemiology and management of patients with systemic vasculitis. In parallel, new insights have been provided on systemic vasculitis pathogenetic mechanisms, possible new therapeutic targets, and newer glucocorticoid-sparing treatments with better safety profiles. As in the previous annual reviews of this series, in this review we will provide a critical digest of the most recent literature regarding pathophysiology, clinical manifestations, diagnostic tools and treatment options in small- and large-vessel vasculitis focusing on precision medicine in vasculitis.

DOI: https://doi.org/10.55563/clinexprheumatol/zf4daj

Rheumatology Article