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Paediatric Rheumatology

 

Optical coherence tomography for the screening of anterior chamber inflammation in paediatric patients diagnosed with juvenile idiopathic arthritis

1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12

 

  1. Paediatric Ophthalmology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, Spain. cristinadps90@gmail.com
  2. Paediatric Ophthalmology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, Spain.
  3. Paediatric Ophthalmology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, Spain.
  4. Paediatric Ophthalmology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, Spain.
  5. Paediatric Ophthalmology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, Spain.
  6. Paediatric Ophthalmology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, Spain.
  7. Paediatric Rheumatology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat; Department of Surgery and Surgical Specializations, Obstetrics and Paediatrics, Universitat de Barcelona, and Grup d’Estudi per Malalties per Disfunció Immune en Pediatria (GEMDIP), Institut de Recerca Sant Joan de Déu (IRSJD), Esplugues de Llobregat, Spain.
  8. Paediatric Rheumatology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, and Grup d’Estudi per Malalties per Disfunció Immune en Pediatria (GEMDIP), Institut de Recerca Sant Joan de Déu (IRSJD), Esplugues de Llobregat, Spain.
  9. Paediatric Rheumatology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, and Grup d’Estudi per Malalties per Disfunció Immune en Pediatria (GEMDIP), Institut de Recerca Sant Joan de Déu (IRSJD), Esplugues de Llobregat, Spain.
  10. Paediatric Rheumatology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, and Grup d’Estudi per Malalties per Disfunció Immune en Pediatria (GEMDIP), Institut de Recerca Sant Joan de Déu (IRSJD), Esplugues de Llobregat, Spain.
  11. Paediatric Rheumatology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat; Grup d’Estudi per Malalties per Disfunció Immune en Pediatria (GEMDIP), Institut de Recerca Sant Joan de Déu (IRSJD), Esplugues de Llobregat; and Rheumatology Unit, Hospital Clínic de Barcelona, Spain.
  12. Paediatric Ophthalmology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, Spain.

CER17278
2024 Vol.42, N°7
PI 1507, PF 1512
Paediatric Rheumatology

purchase article

PMID: 38819950 [PubMed]

Received: 07/11/2023
Accepted : 05/02/2024
In Press: 21/05/2024
Published: 18/07/2024

Abstract

OBJECTIVES:
To evaluate the effectiveness of the anterior segment optical coherence tomography (AS-OCT) for the screening of anterior uveitis in children diagnosed with juvenile idiopathic arthritis (JIA).
METHODS:
A cross-sectional, observational, non-randomised study was conducted in JIA patients younger than 18 years. All patients underwent anterior segment (AS-OCT) and macular OCT.
RESULTS:
A total of 300 eyes of 150 patients diagnosed with JIA were included; 74% were females, and mean age was 11.12 ± 3.51 years old (range 4.13–18.60). In the slit-lamp examination, anterior uveitis was diagnosed in 16 eyes. In the AS-OCT, anterior uveitis was suspected in 27 eyes; cells were detected in 27 eyes and retrokeratic precipitates in 5 eyes. Sensitivity was 0.94 and specificity was 0.96, positive predictive value was 0.59 and negative predictive value was 0.99, and Kappa-Cohen index was 0.71.
CONCLUSIONS:
AS-OCT could be considered for the screening of anterior segment uveitis in children diagnosed with JIA.

DOI: https://doi.org/10.55563/clinexprheumatol/t7pn4v

Rheumatology Article