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Environmental Rheumatology

 

The great challenge: bone fragility and environment

1, 2

 

  1. Rheumatology Unit, Azienda Universitario Ospedaliera di Pisa, Italy. mmazzant@int.med.unipi.it
  2. Rheumatology Unit, Azienda Universitario Ospedaliera di Pisa, Italy.

CER17630
2024 Vol.42, N°9
PI 1714, PF 1719
Environmental Rheumatology

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PMID: 39008293 [PubMed]

Received: 03/03/2024
Accepted : 07/06/2024
In Press: 15/07/2024
Published: 23/09/2024

Abstract

Osteoporosis is a worldwide common disease characterised by reduced bone mass and increased risk of fractures. Many genetic variants are associated with the disease, but they account for only a small percentage of variance in individual bone mineral density and fragility fracture risk. Only recently have researchers recognised the role of a broad variety of environmental factors in the pathogenesis of osteoporosis, which has led to a further step: how genetic and environmental factors can interact, which is the next frontier in research on bone fragility.

DOI: https://doi.org/10.55563/clinexprheumatol/7azn44

Rheumatology Article