One year in review
Pathogenesis of rheumatoid arthritis: one year in review 2024
A. D'orazio1, A.L. Cirillo2, G. Greco3, E. Di Ruscio4, M. Latorre5, F. Pisani6, A. Alunno7, I. Puxeddu8
- Immuno-Allergology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
- Immuno-Allergology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
- Immuno-Allergology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
- Department of Life, Health & Environmental Sciences, University of L’Aquila; Internal Medicine and Nephrology Division, ASL 1 Avezzano-Sulmona-L’Aquila, San Salvatore Hospital, L’Aquila, Italy.
- Pulmonology Unit, Department of Medical Specialties, Nuovo Ospedale Apuano, Massa, Italy.
- Immuno-Allergology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
- Department of Life, Health & Environmental Sciences, University of L’Aquila; Internal Medicine and Nephrology Division, ASL 1 Avezzano-Sulmona-L’Aquila, San Salvatore Hospital, L’Aquila, Italy.
- Immuno-Allergology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy. ilaria.puxeddu@unipi.it
CER18131
2024 Vol.42, N°9
PI 1707, PF 1713
One year in review
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PMID: 39315569 [PubMed]
Received: 30/08/2024
Accepted : 06/09/2024
In Press: 23/09/2024
Published: 23/09/2024
Abstract
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterised by joint destruction and extra-articular manifestations. Different cells and soluble components of the innate as well as adaptive immune system actively contribute to the amplification and perpetuation of the inflammatory processes and structural changes. To date, the knowledge on the mechanisms involved in RA pathogenesis is increasingly precise, mainly due to the recent data obtained from studies on genetics and molecular and cellular biology. In this review article we summarised the new insights into RA pathogenesis from original research articles published in the last year.
