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One year in review

 

Systemic vasculitis: one year in review 2025


1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17

 

  1. School of Medicine, University of Milano-Bicocca, Milan, and Rheumatology Unit, IRCSS San Gerardo dei Tintori, Monza, Italy. paolo.delvino@unimib.it
  2. Rheumatology Unit, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Italy.
  3. Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda USL, IRCCS Reggio Emilia, Italy.
  4. Clinical Immunology, Allergy and Advanced Biotechnologies Unit, Azienda USL, IRCCS Reggio Emilia, Italy.
  5. Rheumatology Unit, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Italy.
  6. Rheumatology Unit, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Italy.
  7. Rheumatology Unit, Azienda USL IRCCS Reggio Emilia and University of Modena and Reggio Emilia, Italy.
  8. Immunorheumatology Research Laboratory, IRCCS Istituto Auxologico Italiano, Milan, Italy.
  9. Rheumatology Unit, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Italy.
  10. Rheumatology Unit, Azienda USL IRCCS Reggio Emilia and University of Modena and Reggio Emilia, Italy.
  11. Rheumatology Unit, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Italy.
  12. Rheumatology Unit, Azienda USL IRCCS Reggio Emilia and University of Modena and Reggio Emilia, Italy.
  13. Rheumatology Unit, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Italy.
  14. Rheumatology Unit, Azienda Ospedaliero-Universitaria Pisana, University of Pisa, Italy.
  15. Division of Rheumatology, Department of Medicine (DMED), Academic Hospital Santa Maria della Misericordia, ASUFC, University of Udine, Italy.
  16. Division of Rheumatology, Department of Medicine (DMED), Academic Hospital Santa Maria della Misericordia, ASUFC, University of Udine, Italy.
  17. Rheumatology Unit, Azienda USL IRCCS Reggio Emilia and University of Modena and Reggio Emilia, Italy.

CER18673
2025 Vol.43, N°4
PI 0553, PF 0562
One year in review

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PMID: 40153326 [PubMed]

Received: 01/03/2025
Accepted : 10/03/2025
In Press: 25/03/2025
Published: 08/04/2025

Abstract

Systemic vasculitides encompass a spectrum of inflammatory disorders affecting several organs and districts, with significant implications for morbidity and mortality. This annual review provides an updated overview of key advancements in vasculitis research, including emerging biomarkers, novel insights into pathogenesis, and therapeutic innovations in both large and small vessel vasculitis. Particular attention is given to emerging concepts, including the role of cellular senescence and stromal cells in vascular inflammation, the expanding spectrum of single-organ vasculitis, and the growing recognition of VEXAS syndrome as a vasculitis-related entity.

DOI: https://doi.org/10.55563/clinexprheumatol/oyqz1p

Rheumatology Article