Review
Systemic sclerosis: one year in review 2025
M. Di Battista1, G. Lepri2, V. Codullo3, L. Bianchessi4, G. Ghezzi5, A. Della Rossa6, S. Guiducci7, F. Del Galdo8
- Rheumatology Unit, University of Pisa, Italy.
- Department of Experimental and Clinical Medicine, University of Florence, Section of Rheumatology, AOU Careggi, Florence, Italy.
- Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
- Rheumatology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
- Rheumatology Unit, University of Pisa, Italy.
- Rheumatology Unit, University of Pisa, Italy. a.dellarossa@ao-pisa.toscana.it
- Department of Experimental and Clinical Medicine, University of Florence, Section of Rheumatology, AOU Careggi, Florence, Italy.
- Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK.
CER18774
2025 Vol.43, N°8
PI 1369, PF 1379
Review
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PMID: 40737082 [PubMed]
Received: 29/03/2025
Accepted : 16/04/2025
In Press: 25/07/2025
Published: 01/08/2025
Abstract
Systemic sclerosis is a rare and chronic connective tissue disease with a complex pathogenesis and highly heterogeneous clinical manifestations. Although significant progress has been made in understanding its underlying mechanisms, early diagnosis and therapeutic strategies, SSc remains a clinical challenge. Each year, several studies explore new insights into its pathogenesis, organ involvement, and treatment. This review provides an overview of the most relevant studies published in the literature in 2024.
