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Anti-CD19 chimeric antigen receptor T cell therapy achieved rapid and sustained remission in a patient with systemic lupus erythematosus-associated refractory immune thrombocytopenia


1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14

 

  1. Biotherapy Center and Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  2. Department of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  3. Biotherapy Center and Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  4. Department of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  5. Department of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  6. Biotherapy Center and Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  7. Biotherapy Center and Cancer Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  8. Department of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  9. Juventas Cell Therapy, Tianjin, China.
  10. Juventas Cell Therapy, Tianjin, China.
  11. Juventas Cell Therapy, Tianjin, China.
  12. Department of Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  13. Department of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. fccliusy2@zzu.edu.cn
  14. Biotherapy Center and Cancer Center, The First Affiliated Hospital of Zhengzhou University; Tianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Zhengzhou University; School of Life Sciences, Zhengzhou University; and School of Public Health, Zhengzhou University, Zhengzhou, China. yizhang@zzu.edu.cn

CER18812
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PMID: 40470549 [PubMed]

Received: 08/04/2025
Accepted : 12/05/2025
In Press: 31/05/2025

Rheumatology Article