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Targeting IL-6 in treatment-resistant Blau syndrome: clinical and laboratory improvement following tocilizumab

1, 2, 3, 4, 5, 6

 

  1. Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena; and Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases (RITA) Center], Policlinico Le Scotte, Siena, Italy.
  2. Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena; and Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases (RITA) Center], Policlinico Le Scotte, Siena, Italy.
  3. Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena; and Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases (RITA) Center], Policlinico Le Scotte, Siena, Italy.
  4. Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena; and Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases (RITA) Center], Policlinico Le Scotte, Siena, Italy.
  5. Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena; and Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases (RITA) Center], Policlinico Le Scotte, Siena, Italy. cantariniluca@hotmail.com
  6. Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena; and Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases (RITA) Center], Policlinico Le Scotte, Siena, Italy.

CER20000
2026 Vol.44, N°10
PI 2186, PF 2187
Letters to the Editor

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Received: 03/04/2026
Accepted : 26/06/2026
In Press: 26/10/2026
Published: 26/10/2026

DOI: https://doi.org/10.55563/clinexprheumatol/c0f7fy

Rheumatology Article