HIV/AIDS: epidemic update, new treatment strategies and impact on autoimmunity

CER3235
2008 Vol.26, N°1 ,Suppl.48
PI 0048, PF 0052
Review

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PMID: 18570754 [PubMed]

Abstract

ABSTRACT: Human Immunodeficiency Virus (HIV) infection represents one of the most serious challenges to global public health, since more than 30 million people are living with HIV/AIDS worldwide. Highly active antiretroviral treatment (HAART) introduction has dramatically changed the mortality and morbidity of HIV-affected subjects in industrialized countries but has implied an evolution of many HIV-related aspects, both in the utilisation of new antiretroviral drugs options and in the newly-observed spectrum of HIV-associated diseases, including the rheumatic pathology. Current epidemiological, therapeutic, autoimmune and rheumatic aspects of HIV-1 infection are here discussed.