Case Reports
Successful use of anakinra to treat refractory Schnitzler`s syndrome
F. Dybowski, N. Sepp, H.J. Bergerhausen, J. Braun
CER3263
2008 Vol.26, N°2
PI 0354, PF 0357
Case Reports
Free to view
(click on article PDF icon to read the article)
PMID: 18565263 [PubMed]
Abstract
ABSTRACT: Schnitzler`s syndrome is a rather rare disease which may appear in a rheumatologist`s office because patients often report rheumatic symptoms with joint, bone and muscle pain. However, it is characterized by chronic urticaria, recurrent fever, liver and spleen enlargement, osteosclerosis, and lymphadenopathy, in conjunction with a serum IgM M component. A patient who had been treated with relatively high doses of corticosteroids for 10 years with insufficient response was treated with the IL-1 receptor antagonist anakinra, this led to a complete resolution of symptoms.
