Case Reports
Axonal neuropathy with prolonged sulphasalazine use
M. Liedorp, A.E. Voskuyl, B.W. Van Oosten
CER3359
2008 Vol.26, N°4
PI 0671, PF 0672
Case Reports
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PMID: 18799104 [PubMed]
Abstract
Sulphasalazine, one of the 5-amino-salicylates, is widely used for the treatment of inflammatory bowel diseases and arthritis. Among the reported adverse effects are blood dyscrasias and hepatic failure. Peripheral neuropathy has been reported as a rare adverse drug reaction to sulphasalazine. Most reported patients developed symptoms several weeks after onset of treatment. We describe a patient with an axonal polyneuropathy that occurred after two years of treatment with sulphasalazine.
