Case Reports
HLA-B*2709 and lack of susceptibility to sacroiliitis: further support from the clinic
A. Cauli, A. Vacca, G. Dessole, M.T. Fiorillo, G. Porru, V. Ibba, V. Mura, M. Piga, R. Sorrentino, A. Mathieu
CER3480
2008 Vol.26, N°6
PI 1111, PF 1112
Case Reports
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PMID: 19210881 [PubMed]
Abstract
ABSTRACT:Interferons (IFN) are well known triggers of immunomediated diseases in genetically predisposed subjects. We describe the unique case of a HLA-B*2709 positive subject who underwent IFN-α treatment for essential thrombocythemia and developed arthritis of the proximal interphalangeal joints of the hands but not sacroiliitis. The possible mechanisms of IFN-induced arthritis are discussed.
