Bone mineral density in patients with rapidly destructive or common hip osteoarthritis

CER3549
2009 Vol.27, N°2
PI 0337, PF 0339
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PMID: 19473579 [PubMed]

Abstract

BACKGROUND:Recent findings that subchondral insufficiency fracture in the femoral head may precede rapid chondrolysis suggest a role for systemic low bone mass in the genesis of rapidly destructive hip osteoarthritis (RDHOA).OBJECTIVES:
To compare bone mineral density (BMD) in females with RDHOA and those with common hip osteoarth-ritis (OA).
METHODS:
This prospective case-control study involved 26 females with RDHOA recruited from our institution between March 2000 and November 2006. BMD was measured at the femoral neck and lumbar spine (L1-L4) by dual-energy x-ray absorptiometry. For comparison, BMD was measured in 33 women with common hip OA who were scheduled for primary total hip arthroplasty.
RESULTS:
Patients with RDHOA and those with common hip OA were similar in age (74.9±9.9 vs. 74.7±8.8 years) and BMI (26.3±4.3 vs. 26.3±5 g/m2) and did not differ in mean BMD at the lumbar spine (1.0±0.2 vs. 1.1±0.2 g/cm2; mean T-score: -0.6±1.3 vs. -0.8±1.5) or at the femoral neck (0.7±0.1 vs. 0.8±0.2 g/cm2; mean T-score: -1.5±1.1 vs. -1.4±1.4).
CONCLUSIONS:
The results of this study do not suggest a role for systemic low bone mass in the pathophysiology of RDHOA.