Side effects and management of side effects of methotrexate in rheumatoid arthritis

CER3960
2010 Vol.28, N°5 ,Suppl.61
PI 0095, PF 0101
Review

Free to view
(click on article PDF icon to read the article)

PMID: 21044440 [PubMed]

Received: 28/06/2010
Accepted : 01/09/2010
In Press: 28/10/2010
Published: 28/10/2010

Abstract

Low-dose methotrexate (MTX) remains the first-line treatment option among the disease-modifying antirheumatic drugs in patients with rheumatoid arthritis. However, diverse side effects are the major reason for MTX withdrawal and change of treatment. The following article reviews the published data on general and organ-specific side effects and outlines the current recommendations addressing prevention and management of MTX-associated adverse effects.