Glucocorticoid-induced osteoporosis

CER4719
2011 Vol.29, N°5 ,Suppl.68
PI 0093, PF 0098
Review

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PMID: 22018192 [PubMed]

Received: 29/04/2011
Accepted : 14/09/2011
In Press: 21/10/2011
Published: 21/10/2011

Abstract

Glucocorticoid-induced osteoporosis is one of the most important side-effects of glucocorticoid use, leading to an increased fracture risk. In this review, recent advances in the understanding of the mechanisms of glucocorticoid-induced osteoporosis are summarised. Methods to identify persons at risk for fractures are discussed, as well as the new ACR recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis (2010). Different treatment options are summarised considering the pathogenesis of glucocorticoid-induced osteoporosis. Improved insights into pathogenesis might result in development of new treatment possibilities.