Neuro-Behçet's disease, its mimickers and anti-TNF therapy: a case-based review

CER5617
2013 Vol.31, N°3 ,Suppl.77
PI 0133, PF 0140
Review

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PMID: 23739034 [PubMed]

Received: 10/04/2012
Accepted : 27/02/2013
In Press: 28/05/2013
Published: 09/09/2013

Abstract

When the central nervous system is the primary affected site in an initial attack of Behçet`s disease (BD), the differential diagnosis is particularly challenging. Because the specificity of immunobiologic therapy is growing, the specific diagnosis may impact the chosen therapy. For instance, anti-tumour necrosis factor agents are efficacious in BD but may be harmful in multiple sclerosis or systemic lupus erythematosus. We present two cases with similar neurological features but different diagnosis (BD and systemic lupus erythematosus) as a starting point to review diagnostic and therapeutic approaches for neuro-BD and its differential diagnoses.