Development and validation of the French ASQoL questionnaire

CER631
2010 Vol.28, N°3
PI 0379, PF 0385
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PMID: 20525446 [PubMed]

Received: 19/09/2009
Accepted : 19/01/2010
In Press: 23/06/2010
Published: 23/06/2010

Abstract

OBJECTIVES:
Ankylosing spondylitis (AS) is a chronic condition with significant impact on quality of life. The objective was to cross-culturally adapt into French and validate the ASQoL, an 18-item disease-specific self-report questionnaire.
METHODS:
Cross-cultural adaptation according to published guidelines used forward and backward translations, with an emphasis on expert committee informed decision making. A sample of active AS French patients answered the questionnaire twice, two weeks apart. A transition question helped identify those with no or some change over time.
RESULTS:
Cross-cultural adaptation resulted in rewording outcome categories from yes/no into true/false to better suit the French context. In 139 patients (mean age 40.9 years, 54.6% males) with active disease (mean BASDAI 4.8), the mean ASQoL score was 10.0. A 2-parameter Rasch model confirmed unidimensionality (chi-square fit p=0.86) with good item discrimination. Internal consistency was high (Cronbach`s alpha 0.9). Convergent validity was ascertained by high correlation of ASQoL score with disease activity measures (r=0.57 to 0.79). Test-retest reproducibility was satisfactory (ICC 0.89). Responsiveness was moderate (SRM 0.44) in patients improving and good (SRM 0.68) in patients worsening over the period.
CONCLUSIONS:
These results show equivalence in content and validity of the cross-culturally adapted ASQoL for French speaking settings.