Exacerbation of interstitial granulomatous dermatitis with arthritis by anakinra in a patient with diffuse large B-cell lymphoma

CER6478
2014 Vol.32, N°2
PI 0259, PF 0261
Case Reports

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PMID: 24480300 [PubMed]

Received: 22/03/2013
Accepted : 02/07/2013
In Press: 30/01/2014
Published: 09/04/2014

Abstract

Interstitial granulomatous dermatitis with arthritis (IGDA) is a rare idiopathic skin disorder with variable cutaneous expression, typically associated with a seronegative arthritis. Histopathology of this disorder reveals a granulomatous infiltrate with foci of collagen degeneration in the deep reticular dermis. We present a case of IGDA in a 56-year-old man with diffuse large B-cell lymphoma, exacerbated by the administration of anakinra.