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Evaluation of a simplified version of the Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) comprising 5 joints (RAMRIS5)

1, 2, 3, 4, 5, 6, 7, 8, 9

 

  1. Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  2. Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  3. Department of Rheumatology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  4. Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  5. Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  6. Institute of Biometry and Epidemiology, German Diabetes Centre, Dusseldorf, Germany.
  7. Department of Rheumatology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  8. Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
  9. Department of Rheumatology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.

CER7843
2015 Vol.33, N°2
PI 0209, PF 0215
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PMID: 25664925 [PubMed]

Received: 13/08/2014
Accepted : 01/12/2014
In Press: 29/01/2015
Published: 10/04/2015

Abstract

OBJECTIVES:
The objective of this study was to evaluate a simplified version of the Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) reduced to five joints of the hand (RAMRIS5).
METHODS:
94 patients with rheumatoid arthritis (62 female; age 59±12 years, range 25–83 years; disease duration 60±90 months (median: 22 months, first quartile: 7 months, third quartile: 66 months) from the REMISSION PLUS study cohort who had complete files on C-reactive protein (CRP) levels and Disease Activity Score of 28 joints (DAS28) and complete MRI of the clinical dominant hand at baseline and after one year under anti-rheumatic therapy (follow-up time 12.5±1.1 months) in a dedicated extremity MRI scanner at 0.2T were included in this retrospective study.
RESULTS:
There was a strong correlation between RAMRIS5 and the RAMRIS sum-score for all patients (r=0.87, p<0.001) at baseline and follow-up (r=0.87, p<0.001). Among the subscores there was a significant correlation between RAMRIS5 and RAMRIS-MCP (baseline: r=0.66, p<0.001; follow-up: r=0.74, p<0.001) as well as between RAMRIS5 and RAMRIS-wrist (baseline: r=0.72, p<0.001, follow-up: r=0.69, p<0.001) at baseline and follow-up.
CONCLUSIONS:
RAMRIS5, a modified shorter RAMRIS score based on five joints of the hand is a viable tool for semi-quantitative assessment of joint damage in RA. This abbreviated score might reduce the time needed for image analysis in MRI-controlled studies in RA and might facilitate the use of MRI in studies on therapy response assessment in RA.

Rheumatology Article