impact factor, citescore
logo
In press
In Press
Recent issue
Recent issue
Recent Supplement
Recent supplement
archives
Archives
articles free
Free to view
Search
Search
 

Paediatric Rheumatology

 

Development of a medication adherence scale for familial Mediterranean fever (MASIF) in a cohort of Turkish children

1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32

 

  1. Gulhane Military Medical Academy, Department of Family Medicine, Ankara, Turkey.
  2. Gulhane Military Medical Faculty, Department of Biostatistics, Ankara, Turkey.
  3. Gulhane Military Medical Academy, School of Nursing, Ankara, Turkey, Turkey.
  4. Gulhane Military Medical Faculty, Department of Pediatrics, Ankara, Turkey.
  5. Ege University Faculty of Medicine, Pediatric Rheumatology, Izmir, Turkey.
  6. Kanuni Sultan Suleyman Research and Training Hospital, Pediatric Nephrology-Rheumatology, Istanbul, Turkey.
  7. Dokuz Eylul University Hospital, Department of Pediatrics, İzmir, Turkey.
  8. Gulhane Military Medical Faculty, Department of Pediatrics, Ankara, Turkey.
  9. Sisli Etfal Education and Research Hospital, Department of Pediatrics, Istanbul, Turkey.
  10. Sisli Etfal Education and Research Hospital, Department of Pediatrics, Istanbul, Turkey.
  11. Dokuz Eylul University Hospital, Department of Pediatrics, İzmir, Turkey.
  12. Istanbul University, Department of Pediatrics, Istanbul, Turkey.
  13. Uludag University Medical Faculty, Dept. of Pediatric Rheumatology, Bursa, Turkey.
  14. Akdeniz University, Department of Pediatrics, Mersin, Turkey.
  15. Pamukkale University Medical Faculty, Dept. of Paediatrics, Denizli, Turkey.
  16. Ege University Faculty of Medicine, Pediatric Rheumatology, Izmir, Turkey.
  17. Erciyes University Medical Faculty, Department of Paediatrics, Kayseri, Turkey.
  18. Gulhane Military Medical Faculty, Department of Pediatrics, Ankara, Turkey.
  19. Gulhane Military Medical Faculty, Department of Pediatrics, Ankara, Turkey.
  20. Ministry of Health Dıskapı Children’s Hospital, Paediatric Nephrology, Ankara, Turkey.
  21. Selcuk University, Department of Paediatrics, Ankara, Turkey.
  22. Gazi Universty, Department of Paediatrics, Ankara, Turkey.
  23. Inonu University, Paediatric Nephrology, Malatya, Turkey.
  24. Gulhane Military Medical Academy, Department of Family Medicine, Ankara, Turkey.
  25. Gulhane Military Medical Academy, Department of Family Medicine, Ankara, Turkey.
  26. Gulhane Military Medical Academy, Department of Family Medicine, Ankara, Turkey.
  27. Gulhane Military Medical Faculty, Department of Pediatrics, Ankara, Turkey.
  28. Dokuz Eylul University Hospital, Department of Pediatrics, İzmir, Turkey.
  29. Istanbul University, Department of Pediatrics, Istanbul, Turkey.
  30. Gulhane Military Medical Faculty, Paediatric Rheumatology Unit, Ankara, Turkey.
  31. Hacettepe University, Paediatric Nephrology and Rheumatology Unit, Ankara, Turkey.
  32. Gulhane Military Medical Faculty, Paediatric Rheumatology Unit, Ankara; and Gulhane Military Medical Academy, FMF Arthritis Vasculitis and Orphan disease Research in Paediatric Rheumatology, Ankara, Turkey. erkandemirkaya@yahoo.com

for FMF Arthritis Vasculitis and Orphan disease Research in Paediatric Rheumatology (FAVOR)

CER7903
2015 Vol.33, N°6 ,Suppl.94
PI 0156, PF 0162
Paediatric Rheumatology

Free to view
(click on article PDF icon to read the article)

PMID: 26393894 [PubMed]

Received: 08/09/2014
Accepted : 05/06/2015
In Press: 22/09/2015
Published: 04/11/2015

Abstract

OBJECTIVES:
To develop and assess the validity and reliability of an adherence scale concerning medical treatment in paediatric FMF patients.
METHODS:
The Medication Adherence Scale in FMF Patients (MASIF) is a 18-item questionnaire that evaluates adherence to medication in four domains. Validation of the instrument was accomplished in paediatric FMF patients (aged 2–18 years) under medication at least for 6 months. The first step was to build up the scale through qualitative approach (with interviews using semi-structured questions). Validation analyses included assessment of feasibility, face and content validity; construct validity, internal consistency and test-retest reliability.
RESULTS:
One hundred and fifty patients with FMF were enrolled in the study. The mean age of the patients was 11.11±4.02 years and 48.7% of them were male. The MASIF was found to be feasible and valid for both face and content. It correlated with the Morisky Medication Adherence Scale as a gold standard thereby demonstrating good construct validity (r=0.515, p<0.001). Assessment of content validity identified four subscales. The internal consistency, Cronbach’s alpha was 0.728. There was a positive and significant correlation between test and retest scores (r=0.843; p<0.001). Also, a significant correlation between parents’ and children’s reports (r=0.781, p<0.001).
CONCLUSIONS:
Based on these results, the use of this scale to assess and follow up the adherence to treatment in paediatric FMF patients under medical treatment is recommended.

Rheumatology Article