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Prevalence and clinical characteristics of psoriasis in spondyloarthritis: a descriptive analysis of 275 patients


1, 2, 3, 4, 5, 6, 7, 8

 

  1. Descartes Univ., Medicine Faculty; APHP, Rheumatology B Dept., Cochin Hosp., Paris; & Sorbonne Univ., UPMC Univ Paris 06, GRC-08, Inst. P. Louis d’Epidémiologie et de Santé Publique, Paris; Pitié-Salpétrière Hosp., AP-HP, Rheumatology Dept., Paris, France
  2. Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
  3. Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
  4. Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
  5. Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
  6. Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
  7. Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
  8. Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d’Epidémiologie et de Santé Publique, Paris; Pitié-Salpétrière Hospital, AP-HP, Rheumatology Department, Paris, France.

CER8423
2016 Vol.34, N°1
PI 0082, PF 0087
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PMID: 26842749 [PubMed]

Received: 05/03/2015
Accepted : 02/09/2015
In Press: 02/02/2016
Published: 10/02/2016

Abstract

OBJECTIVES:
To assess the prevalence of psoriasis among a cohort of patients with spondyloarthritis (SpA), to describe the clinical characteristics of psoriasis and associations with other manifestations.
METHODS:
This is a retrospective single-centre observational study. The patients were diagnosed with definite SpA (expert opinion), either axial or peripheral. Each patient underwent a direct interview by a physician. The data regarding history of psoriasis and its clinical characteristics were collected. Univariate and multivariate analyses of patients with versus without psoriasis were carried out.
RESULTS:
In all, 275 SpA patients were assessed: mean disease duration 16.7±11.8 years, 61.4% were men, 69.1% were diagnosed as axial SpA and 17.8% as peripheral SpA. In all, 84 patients (30.5%) had present or past psoriasis. The prevalence of psoriasis was high whatever the clinical presentation. Psoriasis was present before or concomitantly to diagnosis of SpA in 59/84 patients (70.2%). The most common types of psoriasis were plaque (66.7% of patients with psoriasis) and scalp psoriasis (65.5%). Other localisations were not rare, including palmoplantar pustulosis (20.2%) or nail psoriasis (19.1%). Patients with versus without psoriasis differed only through a lower proportion of radiological sacroiliitis (57.5% vs. 81.3 %, p<0.001).
CONCLUSIONS:
With a prevalence of 30.5%, i.e. ten times higher than in the general population, this study confirms that psoriasis is a frequent and early manifestation in SpA and that a systematic search for psoriasis (e.g. scalp) is relevant in SpA for clinical practice, whatever the clinical presentation of SpA.

Rheumatology Article