γδ T-cells: basic features and potential role in vasculitis

CER879
2010 Vol.28, N°1 ,Suppl.57
PI 0104, PF 0109
Review

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PMID: 20412714 [PubMed]

Received: 03/02/2010
Accepted : 17/02/2010
In Press: 22/04/2010
Published: 22/04/2010

Abstract

γδ T-cells are a numerically small subset of T-cells with distinct features. They recognise antigens that are not seen by other immune cells. At the functional level, γδ T-cells share some features with αβ T-cells but also exert functions that are otherwise performed by specialised subsets of αβ T-cells (e.g. IL-17 production, regulatory activity). We discuss the potential role of γδ T-cells in various clinical forms of vasculitis.