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One year in review 2015: systemic lupus erythematosus


1, 2, 3, 4, 5, 6

 

  1. Department of Rheumatology, University of Perugia, Perugia, Italy.
  2. Department of Rheumatology, University of Perugia, Perugia, Italy.
  3. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy.
  4. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
  5. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy.
  6. Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, and Genetic, Oncology and Clinical Medicine (GenOMeC) PhD, University of Siena, Italy.

CER8666
2015 Vol.33, N°3
PI 0414, PF 0425
Review

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PMID: 26106941 [PubMed]

Received: 05/06/2015
Accepted : 06/06/2015
In Press: 22/06/2015
Published: 22/06/2015

Abstract

Systemic lupus erythematosus is a multiorgan autoimmune disease with a highly variable clinical course, typically involving women in childbearing age. At present, many aspects of its pathogenesis still remain unclear. Moreover, although a significant increase of patient survival has been observed in the last decades, morbidity and mortality remain high. Finally, SLE impacts negatively on the health-related quality-of-life of patients. Therefore, multiple aspects of SLE still remain challenging and it continues to be the object of both clinical and translational clinical research. Herewith, we provide a critical digest of the recent literature on this topic.

Rheumatology Article