Paediatric Rheumatology
Incidence, epidemiology and clinical features of Kawasaki disease in Catalonia, Spain
J. Sánchez-Manubens1, J. Antón2, R. Bou3, E. Iglesias4, J. Calzada-Hernandez5
- Unitat de Reumatologia Pediàtrica, Servei de Pediatria, Hospital Universitari Parc Taulí, Sabadell, Barcelona; and Unitat de Reumatologia Pediàtrica, Servei de Pediatria, Hosp. Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain. jsanchez@tauli.cat
- Unitat de Reumatologia Pediàtrica, Servei de Pediatria, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
- Unitat de Reumatologia Pediàtrica, Servei de Pediatria, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
- Unitat de Reumatologia Pediàtrica, Servei de Pediatria, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
- Unitat de Reumatologia Pediàtrica, Servei de Pediatria, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
and the Kawasaki Disease in Catalonia Working Group
CER8780
2016 Vol.34, N°3 ,Suppl.97
PI 0139, PF 0144
Paediatric Rheumatology
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PMID: 26939753 [PubMed]
Received: 14/07/2015
Accepted : 02/10/2015
In Press: 03/03/2016
Published: 29/05/2016
Abstract
OBJECTIVES:
To assess the incidence, epidemiology and clinical features of Kawasaki disease (KD) in Catalonia (northeast region of Spain).
METHODS:
This was an observational population-based study including all Paediatric Units in Catalonia, under both public and private management. Retrospective data retrieval was performed for 10 years (2004–2013). A 12-month (March 2013 to March 2014) prospective collection of new cases of KD was carried out to determine the incidence of KD.
RESULTS:
Data from 399 patients over the 10-year study period was analysed, revealing that 233 (58.4%) had complete KD, 159 (39.8) incomplete KD and 7 (1.7%) were considered atypical KD. Mean annual incidence was 3.5/105 children <14 years old (yo) and 8/105 children <5 yo (mean age 37±33 months, range 1.3–191.3). KD was more frequent in boys (59.6%, p<0.001) and in rural areas (p<0.001). Patients with IVIG non-responsiveness, need of a 2nd IVIG dose, delay of treatment >10th day of illness, ages <1 yo and >8 yo and the presence of sterile piuria, aseptic meningitis, abdominal pain and uveitis at diagnosis were found to have higher risk of coronary aneurisms (CAA) (p<0.05).
CONCLUSIONS:
This is the first population-based study on the epidemiology of KD in the western Mediterranean area. Incidence, clinical features and treatment plans in our cohort are similar to those described in other European studies.