Skin and nail manifestations in psoriatic arthritis
Pathogenesis and treatment of psoriasis: exploiting pathophysiological pathways for precision medicine
W. Alwan1, F.O. Nestle2
- St. John’s Institute of Dermatology, Guy’s and St. Thomas’ Hospitals NHS Foundation Trust, London, UK.
- St. John’s Institute of Dermatology, Guy’s and St. Thomas’ Hospitals NHS Foundation Trust, London, UK. frank.nestle@kcl.ac.uk
CER8924
2015 Vol.33, N°5 ,Suppl.93
PI 0002, PF 0006
Skin and nail manifestations in psoriatic arthritis
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PMID: 26472336 [PubMed]
Received: 02/09/2015
Accepted : 02/09/2015
In Press: 15/10/2015
Published: 16/10/2015
Abstract
Psoriasis is a common, chronic inflammatory skin disease associated with multi-system manifestations including arthritis and obesity. Our knowledge of the aetiology of the condition, including the key genomic, immune and environmental factors, has led to the development of targeted, precision therapies that alleviate patient morbidity. This article reviews the key pathophysiological pathways and therapeutic targets and highlights future areas of interest in psoriasis research.
