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One year in review

 

Fibromyalgia: one year in review 2023

1, 2, 3, 4, 5, 6, 7, 8, 9, 10

 

  1. Rheumatology Department, IRCCS Galeazzi-Sant’Ambrogio Hospital, Milan, Italy. vale.gio@fastwebnet.it
  2. Rheumatology Department, IRCCS Galeazzi-Sant’Ambrogio Hospital, Milan, Italy.
  3. Rheumatology Unit, Internal Medicine Department, ASST Settelaghi, Ospedale Di Circolo - Fondazione Macchi, Varese, Italy.
  4. Rheumatology Department, IRCCS Galeazzi-Sant’Ambrogio Hospital, Milan, Italy.
  5. Dipartimento di Scienze Cliniche, Internistiche, Anestesiologiche e Cardiovascolari-Reumatologia, Sapienza University of Rome, Italy.
  6. Rheumatology Department, IRCCS Galeazzi-Sant’Ambrogio Hospital, Milan, Italy.
  7. Rheumatology Unit, Department of Internal and Experimental Medicine, University of Messina, Italy.
  8. Department of Clinical Neurosciences, Hermanas Hospitalarias, Villa San Benedetto Menni Hospital, Como, and Humanitas Clinical and Research Centre, Milan, Italy.
  9. Rheumatology Clinic, Ospedale Carlo Urbani, Università Politecnica delle Marche, Jesi, Ancona, Italy.
  10. Rheumatology Department, IRCCS Galeazzi-Sant’Ambrogio Hospital, Milan, Italy.

CER16897
2023 Vol.41, N°6
PI 1205, PF 1213
One year in review

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PMID: 37378487 [PubMed]

Received: 07/06/2023
Accepted : 12/06/2023
In Press: 28/06/2023
Published: 28/06/2023

Abstract

Fibromyalgia (FM) is a chronic syndrome characterised by widespread pain that affects millions of people worldwide. This article discusses various aspects of FM described in scientific papers published in 2022 and indexed in the PubMed database, including the most recent diagnostic acquisitions (especially in relation to the juvenile form of FM), risk factors, co-morbidities and objective measures. Emphasis is placed on the importance of identifying FM early and improving diagnostic methods (e.g. physical measurements, including walking test performance, hand grip force, and autonomic tests). The article also considers hypotheses concerning the pathophysiology of FM, including the role of inflammation, gut dysbiosis, and neuroinflammation, and possible treatment options, including medications such as antioxidants and kinin antagonists, neurostimulation, and mind-body interventions. Although ketamine, vitamin D, and hormone therapy have shown promise in reducing FM symptoms, further research is needed to optimise their use. Neurostimulation techniques, such as transcutaneous electrical nerve stimulation, transcranial direct-current stimulation and transcranial magnetic stimulation, have been investigated in terms of their efficacy in reducing pain and improving the quality of life. Finally, the role of nutrition is discussed as study findings suggest that weight control, modified high-antioxidant diets, and nutritional supplementation can help to alleviate the symptoms of FM.

DOI: https://doi.org/10.55563/clinexprheumatol/257e99

Rheumatology Article