2025 Vol.43, N°2 - Table of contents
February - Myositis 2025
One year in review
CER18615
2025,43,2
Pg. 0167-0177
Free to view
Idiopathic inflammatory myopathies: one year in review 2024
F. Fattorini, E. Conticini, E. Dourado, F. Bottazzi, L. Bruno, M. Diomedi, J. Schmidt, L. Carli, L. Cavagna, S. Barsotti
DOI: https://doi.org/10.55563/clinexprheumatol/yizkja
F. Fattorini, E. Conticini, E. Dourado, F. Bottazzi, L. Bruno, M. Diomedi, J. Schmidt, L. Carli, L. Cavagna, S. Barsotti
DOI: https://doi.org/10.55563/clinexprheumatol/yizkja
Editorials
CER18287
2025,43,2
Pg. 0178-0183
Free to view
The classification of myositis: setting the stage for a universal terminology
M. Giannini, S. Bhai, O. Boyer, K. Cheng, M. Johari, P. Korsten, J.B. Lilleker, D. Saygin, S. Schlüter, A.J. Van Der Kooi, J. Schmidt
on behalf of the International Myositis Society (iMyoS)
DOI: https://doi.org/10.55563/clinexprheumatol/s80tkm
M. Giannini, S. Bhai, O. Boyer, K. Cheng, M. Johari, P. Korsten, J.B. Lilleker, D. Saygin, S. Schlüter, A.J. Van Der Kooi, J. Schmidt
on behalf of the International Myositis Society (iMyoS)
DOI: https://doi.org/10.55563/clinexprheumatol/s80tkm
CER18436
2025,43,2
Pg. 0184-0185
Free to view
The myositis landscape in clinical trials: 2025 and beyond
G. Zanframundo, V. Codullo, L. Cavagna
DOI: https://doi.org/10.55563/clinexprheumatol/86an43
G. Zanframundo, V. Codullo, L. Cavagna
DOI: https://doi.org/10.55563/clinexprheumatol/86an43
Environmental Rheumatology
CER17788
2025,43,2
Pg. 0186-0192
Free to view
Environmental triggers for idiopathic inflammatory myopathies: unravelling the known and unknown
C. Cardelli, F. Trentin, F. Fattorini, M. Diomedi, E. Laurino, S. Barsotti, M. Mosca, L. Carli
DOI: https://doi.org/10.55563/clinexprheumatol/0x1gob
C. Cardelli, F. Trentin, F. Fattorini, M. Diomedi, E. Laurino, S. Barsotti, M. Mosca, L. Carli
DOI: https://doi.org/10.55563/clinexprheumatol/0x1gob
CER18069
2025,43,2
Pg. 0193-0201
Free to view
Different phenotypic manifestations between Brazilian and Japanese anti-MDA5 antibody-positive dermatomyositis: an international tricentric longitudinal study
M.S. Faria, A. Yoshida, N. Mugii, P.T. Inaoka, T. Matsushita, T. Gono, M. Kuwana, S.K. Shinjo
DOI: https://doi.org/10.55563/clinexprheumatol/9s7djz
M.S. Faria, A. Yoshida, N. Mugii, P.T. Inaoka, T. Matsushita, T. Gono, M. Kuwana, S.K. Shinjo
DOI: https://doi.org/10.55563/clinexprheumatol/9s7djz
Special Article
CER18342
2025,43,2
Pg. 0202-0210
Free to view
The Myositis Clinical Trials Consortium: an international collaborative initiative to promote clinical trials in adult and juvenile myositis
A. Bishnoi, I.Y.K. Tang, A. Yoshida, F.M. Pais, S.Y. Usman, S.A. Dominguez, C.G. Kavadichanda, D. Rivero-Gallegos, E. Dourado, E. Conticini, F. Bozán, G. Tulluru, J.B. Lilleker, K. Sreerama Reddy, O. Landon-Cardinal, R. Smaili, S. Keret, T. Khoo, T.-Y. Lan, V. Leclair, C.V. Oddis, J. Vencovský, M. Kuwana, P.C. Gandiga, R. Aggarwal
Collaborator/s: O. Benveniste, D.B. De Araujo, C. Charles-Schoeman, H. Chinoy, T.J. Corte, M.M. Dimachkie, R.P. Dodiuk-Gad, P. Eichenbrenner, M. Fujimoto, I. García-De la torre, N. Govind, N.A. Goyal, Z. Griger, R.W. Hallowell, M. Hudson, V. Limaye, L. Rajasekhar, M. Lubinus, I.E. Lundberg, S. Malloy, G. Marder, L. Metni, J. Myles, M. Needham, J. Raaphorst, L.G. Rider, J. Rojas-Serrano, J. Schmidt, A. Selva-O’callaghan, S.K. Shinjo, V. Shobha, H. So, I.B. Ventura, S. Venuturupalli, R.A. Vleugels, G. Wang, Q. Wang, E.M. Wilfong, B.M. Feldman, A.M. Huber, H. Kim, S. Kim, A. Ravelli, A. Van royen-Kerkhof
on behalf of the Myositis Clinical Trials Consortium investigators
DOI: https://doi.org/10.55563/clinexprheumatol/k7665a
A. Bishnoi, I.Y.K. Tang, A. Yoshida, F.M. Pais, S.Y. Usman, S.A. Dominguez, C.G. Kavadichanda, D. Rivero-Gallegos, E. Dourado, E. Conticini, F. Bozán, G. Tulluru, J.B. Lilleker, K. Sreerama Reddy, O. Landon-Cardinal, R. Smaili, S. Keret, T. Khoo, T.-Y. Lan, V. Leclair, C.V. Oddis, J. Vencovský, M. Kuwana, P.C. Gandiga, R. Aggarwal
Collaborator/s: O. Benveniste, D.B. De Araujo, C. Charles-Schoeman, H. Chinoy, T.J. Corte, M.M. Dimachkie, R.P. Dodiuk-Gad, P. Eichenbrenner, M. Fujimoto, I. García-De la torre, N. Govind, N.A. Goyal, Z. Griger, R.W. Hallowell, M. Hudson, V. Limaye, L. Rajasekhar, M. Lubinus, I.E. Lundberg, S. Malloy, G. Marder, L. Metni, J. Myles, M. Needham, J. Raaphorst, L.G. Rider, J. Rojas-Serrano, J. Schmidt, A. Selva-O’callaghan, S.K. Shinjo, V. Shobha, H. So, I.B. Ventura, S. Venuturupalli, R.A. Vleugels, G. Wang, Q. Wang, E.M. Wilfong, B.M. Feldman, A.M. Huber, H. Kim, S. Kim, A. Ravelli, A. Van royen-Kerkhof
on behalf of the Myositis Clinical Trials Consortium investigators
DOI: https://doi.org/10.55563/clinexprheumatol/k7665a
Full Papers
CER17426
2025,43,2
Pg. 0211-0220
Free to view
Clinical features and prognosis of idiopathic inflammatory myopathies with coexistent multiple myositis-specific antibodies
X. Liang, J. Wu, H. Ren, M. Li, C. Huang, J.G. Guo, D. Li, J. Li, J. Zhu
DOI: https://doi.org/10.55563/clinexprheumatol/22j41g
X. Liang, J. Wu, H. Ren, M. Li, C. Huang, J.G. Guo, D. Li, J. Li, J. Zhu
DOI: https://doi.org/10.55563/clinexprheumatol/22j41g
CER17365
2025,43,2
Pg. 0221-0229
Free to view
Pleural effusion as a predictor of rapidly progressive interstitial lung disease and mortality in idiopathic inflammatory myopathies
X. Liang, H. Ren, F. Xiao, S. Zheng, R. Wang, C. Huang, J. Guo, J. Li, J. Zhu
DOI: https://doi.org/10.55563/clinexprheumatol/ve77nv
X. Liang, H. Ren, F. Xiao, S. Zheng, R. Wang, C. Huang, J. Guo, J. Li, J. Zhu
DOI: https://doi.org/10.55563/clinexprheumatol/ve77nv
CER17402
2025,43,2
Pg. 0230-0240
Free to view
Self-reported physical activity and fatigue and its associations to anxiety and depression in adult patients with idiopathic inflammatory myopathies:a MIHRA psychological impact and MIHRA exercise and rehabilitation scientific working groups collaboration
K.M. Andreasson, F. Espinosa-Ortega, H. Sandlund, H. Alexanderson
DOI: https://doi.org/10.55563/clinexprheumatol/5u5ah3
K.M. Andreasson, F. Espinosa-Ortega, H. Sandlund, H. Alexanderson
DOI: https://doi.org/10.55563/clinexprheumatol/5u5ah3
CER17588
2025,43,2
Pg. 0241-0250
Free to view
CD44 is associated with muscle inflammation in polymyositis and skin damage in idiopathic inflammatory myopathy
Y. Zhou, Y. Zhao, G. Yin, L. Kang, X. Zhu, Q. Xie
DOI: https://doi.org/10.55563/clinexprheumatol/hlk85n
Y. Zhou, Y. Zhao, G. Yin, L. Kang, X. Zhu, Q. Xie
DOI: https://doi.org/10.55563/clinexprheumatol/hlk85n
CER17836
2025,43,2
Pg. 0251-0259
Free to view
Triple-combination therapy did not improve prognosis in anti-MDA5 positive dermatomyositis: a multicentre longitudinal cohort study
H. You, C. Lv, L. Xu, L. Wang, T. Liu, F. Yuan, W. Yan, H. Wei, J. Wang, D. Meng, W. Tan
DOI: https://doi.org/10.55563/clinexprheumatol/jmpuxa
H. You, C. Lv, L. Xu, L. Wang, T. Liu, F. Yuan, W. Yan, H. Wei, J. Wang, D. Meng, W. Tan
DOI: https://doi.org/10.55563/clinexprheumatol/jmpuxa
CER17844
2025,43,2
Pg. 0260-0268
Free to view
Risk prediction modelling in idiopathic inflammatory myositis-associated interstitial lung disease based on seven factors including serum KL-6 and lung ultrasound B-lines
W. Zhang, G. Huang, S. Zheng, J. Lin, S. Hu, J. Zhuang, Z. Zhou, G. Du, K. Zheng, S. Chen, Q. Zhang, A. Mikish, A.-M. Hoffmann-Vold, M. Kuwana, M. Matucci-Cerinic, D.E. Furst, Y. Wang
DOI: https://doi.org/10.55563/clinexprheumatol/ylf0oe
W. Zhang, G. Huang, S. Zheng, J. Lin, S. Hu, J. Zhuang, Z. Zhou, G. Du, K. Zheng, S. Chen, Q. Zhang, A. Mikish, A.-M. Hoffmann-Vold, M. Kuwana, M. Matucci-Cerinic, D.E. Furst, Y. Wang
DOI: https://doi.org/10.55563/clinexprheumatol/ylf0oe
CER17913
2025,43,2
Pg. 0269-0275
Free to view
Human epididymitis protein 4 as a biomarker of interstitial lung disease in patients with idiopathic inflammatory myopathies
E. Zanatta, B. Moccaldi, A. Martini, L. Ienna, R. Depascale, M. Binda, M. Gatto, M. Zen, M. Tonello, A. Ghirardello, C. Giraudo, E. Balestro, M. Plebani, D. Basso, A. Doria, L. Iaccarino
DOI: https://doi.org/10.55563/clinexprheumatol/s73lah
E. Zanatta, B. Moccaldi, A. Martini, L. Ienna, R. Depascale, M. Binda, M. Gatto, M. Zen, M. Tonello, A. Ghirardello, C. Giraudo, E. Balestro, M. Plebani, D. Basso, A. Doria, L. Iaccarino
DOI: https://doi.org/10.55563/clinexprheumatol/s73lah
CER18176
2025,43,2
Pg. 0276-0281
Free to view
The clinical characteristics of pharyngeal and laryngeal lesions in anti-MDA5-positive dermatomyositis patients
W. Huang, F. Ren, D. Deng, L. Luo, J. Zhou, D. Huang, M. Tian, D. Chen, K. Qian, Y. Jiang, L. Tang
DOI: https://doi.org/10.55563/clinexprheumatol/t0478a
W. Huang, F. Ren, D. Deng, L. Luo, J. Zhou, D. Huang, M. Tian, D. Chen, K. Qian, Y. Jiang, L. Tang
DOI: https://doi.org/10.55563/clinexprheumatol/t0478a
CER18318
2025,43,2
Pg. 0282-0289
Free to view
Utilising bioinformatics and systems biology methods to uncover the impact of dermatomyositis on interstitial lung disease
R. Ding, D. Liang, S. Huang, X. Huang, B. Wei, S. Wan, H. Zhang, Z. Wan
DOI: https://doi.org/10.55563/clinexprheumatol/fok820
R. Ding, D. Liang, S. Huang, X. Huang, B. Wei, S. Wan, H. Zhang, Z. Wan
DOI: https://doi.org/10.55563/clinexprheumatol/fok820
CER17853
2025,43,2
Pg. 0290-0299
Free to view
Infections as a predominant cause of death in adult patients with idiopathic inflammatory myopathies
A.H. Opinc-Rosiak, E.M. Kulesza, A.J. Mikosińska, O.E. Brzezińska, J.S. Makowska
DOI: https://doi.org/10.55563/clinexprheumatol/kcdmct
A.H. Opinc-Rosiak, E.M. Kulesza, A.J. Mikosińska, O.E. Brzezińska, J.S. Makowska
DOI: https://doi.org/10.55563/clinexprheumatol/kcdmct
CER18376
2025,43,2
Pg. 0300-0308
Free to view
Determining patient and carer priorities in inclusion body myositis: a patient-led research study
K.L. Austin, B. Hawkins, K.A. Beer, A.B. Doverty, M. Needham
DOI: https://doi.org/10.55563/clinexprheumatol/5xqelc
K.L. Austin, B. Hawkins, K.A. Beer, A.B. Doverty, M. Needham
DOI: https://doi.org/10.55563/clinexprheumatol/5xqelc
CER18317
2025,43,2
Pg. 0309-0315
Free to view
Challenges in international investigator-led rare disease clinical trials and the case for optimism in inclusion body myositis
M. Needham, U.A. Badrising, K. Beer, A.J. Heim, A. Doverty, A. Panicker, O. Benveniste, M.M. Dimachkie
DOI: https://doi.org/10.55563/clinexprheumatol/dyjcsn
M. Needham, U.A. Badrising, K. Beer, A.J. Heim, A. Doverty, A. Panicker, O. Benveniste, M.M. Dimachkie
DOI: https://doi.org/10.55563/clinexprheumatol/dyjcsn
CER18316
2025,43,2
Pg. 0316-0325
Free to view
Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale
U.A. Badrising, R. Henderson, S. Reddel, A. Corbett, C. Liang, K. Reardon, R. Ghaoui, M. Bulsara, S. Brady, A. Brusch, D. Chan, J.D. Coudert, T. Fairchild, G. Jain, M.C. Kiernan, D. Leonard, T. Lloyd, J. Schmidt, M.P. Mcdermott, L. Sanders, C. Lowe, A.J. Van Der Kooi, C. Weihl, P. Mohassel, M. Simpson, A. Carroll, I. Cooper, K. Beer, K. Hiscock, S. Walters, A. Panicker, A. Doverty, A. Heim, M. Van heur-Neuman, O. Benveniste, M.M. Dimachkie, M. Needham
DOI: https://doi.org/10.55563/clinexprheumatol/zvffa0
U.A. Badrising, R. Henderson, S. Reddel, A. Corbett, C. Liang, K. Reardon, R. Ghaoui, M. Bulsara, S. Brady, A. Brusch, D. Chan, J.D. Coudert, T. Fairchild, G. Jain, M.C. Kiernan, D. Leonard, T. Lloyd, J. Schmidt, M.P. Mcdermott, L. Sanders, C. Lowe, A.J. Van Der Kooi, C. Weihl, P. Mohassel, M. Simpson, A. Carroll, I. Cooper, K. Beer, K. Hiscock, S. Walters, A. Panicker, A. Doverty, A. Heim, M. Van heur-Neuman, O. Benveniste, M.M. Dimachkie, M. Needham
DOI: https://doi.org/10.55563/clinexprheumatol/zvffa0
CER18153
2025,43,2
Pg. 0326-0333
Free to view
TRIM63 and Atrogin-1 are key drivers of systemic and muscle inflammation in patients with idiopathic inflammatory myopathies
A. Absalón-Aguilar, J.J. Torres-Ruiz, N.R. Mejía-Domínguez, A. Pérez-Fragoso, F. Cassiano-Quezada, M. Tapia-Rodríguez, C. Núñez-Alvarez, J. Ríos-Valencia, B. Marquina-Castillo, G. Juarez-Vega, D. Gomez-Martin
DOI: https://doi.org/10.55563/clinexprheumatol/p2lma6
A. Absalón-Aguilar, J.J. Torres-Ruiz, N.R. Mejía-Domínguez, A. Pérez-Fragoso, F. Cassiano-Quezada, M. Tapia-Rodríguez, C. Núñez-Alvarez, J. Ríos-Valencia, B. Marquina-Castillo, G. Juarez-Vega, D. Gomez-Martin
DOI: https://doi.org/10.55563/clinexprheumatol/p2lma6
CER18573
2025,43,2
Pg. 0334-0344
Free to view
Quantitative muscle magnetic resonance imaging as a biomarker for inclusion body myositis in clinical trials: exploring the in vivo effects of arimoclomol
S. Salam, J.M. Morrow, M.P. Mcdermott, N. Zafeiropoulos, J.S. Thornton, S. Shah, S. Wastling, T.Y. Yousry, R.J. Barohn, M.G. Hanna, M.M. Dimachkie, P.M. Machado
DOI: https://doi.org/10.55563/clinexprheumatol/5b9lme
S. Salam, J.M. Morrow, M.P. Mcdermott, N. Zafeiropoulos, J.S. Thornton, S. Shah, S. Wastling, T.Y. Yousry, R.J. Barohn, M.G. Hanna, M.M. Dimachkie, P.M. Machado
DOI: https://doi.org/10.55563/clinexprheumatol/5b9lme
Reviews
CER17256
2025,43,2
Pg. 0345-0353
Free to view
Disease models of myositis: overview of cell culture and rodent systems
M. Hauke, M. Kamiya, C.C. Weihl, J. Schmidt
DOI: https://doi.org/10.55563/clinexprheumatol/4yp71i
M. Hauke, M. Kamiya, C.C. Weihl, J. Schmidt
DOI: https://doi.org/10.55563/clinexprheumatol/4yp71i
CER17712
2025,43,2
Pg. 0354-0363
Free to view
Brepocitinib, a potent and selective TYK2/JAK1 inhibitor: scientific and clinical rationale for dermatomyositis
J.J. Paik, J. Vencovský, C. Charles-Schoeman, G.C. Wright, R.A. Vleugels, A.S. Goriounova, P.N. Mudd, Jr, R. Aggarwal
DOI: https://doi.org/10.55563/clinexprheumatol/eeglsa
J.J. Paik, J. Vencovský, C. Charles-Schoeman, G.C. Wright, R.A. Vleugels, A.S. Goriounova, P.N. Mudd, Jr, R. Aggarwal
DOI: https://doi.org/10.55563/clinexprheumatol/eeglsa
CER18124
2025,43,2
Pg. 0364-0371
Free to view
An update on myositis autoantibodies and insights into pathogenesis
G. Wang, N.J. Mchugh
DOI: https://doi.org/10.55563/clinexprheumatol/kyj2cy
G. Wang, N.J. Mchugh
DOI: https://doi.org/10.55563/clinexprheumatol/kyj2cy
CER18560
2025,43,2
Pg. 0372-0378
Free to view
Imaging evaluation of the upper limbs in inclusion body myositis: an unmet need
S. Salam, J.M. Morrow, S. Shah, M.G. Hanna, M.M. Dimachkie, P.M. Machado
DOI: https://doi.org/10.55563/clinexprheumatol/q7ozm2
S. Salam, J.M. Morrow, S. Shah, M.G. Hanna, M.M. Dimachkie, P.M. Machado
DOI: https://doi.org/10.55563/clinexprheumatol/q7ozm2
Paediatric Rheumatology
CER17663
2025,43,2
Pg. 0379-0386
Free to view
Longitudinal assessment of disease activity and muscle strength in juvenile dermatomyositis: a multicentre registry study
D. Hortelan Antonio, B.O. Carneiro, T.A. Fernandes, A.M. Elias, A.J. Pantoja De Moraes, A.P. Vecchi, A. Cavalcanti, C.N. Rabelo Jr, C.M. Magalhaes, F.R. Sztajnbok, L.M. Carvalho, L. Paim Marques, M.T. Terreri, M.M. Fraga, S.K. De Oliveira, S.B. Sacchetti, S. Appenzeller, T. Robazzi, V.P. Ferriani, C.A. Len, C.A. Silva, C. Saad-Magalhaes
DOI: https://doi.org/10.55563/clinexprheumatol/yrb7m2
D. Hortelan Antonio, B.O. Carneiro, T.A. Fernandes, A.M. Elias, A.J. Pantoja De Moraes, A.P. Vecchi, A. Cavalcanti, C.N. Rabelo Jr, C.M. Magalhaes, F.R. Sztajnbok, L.M. Carvalho, L. Paim Marques, M.T. Terreri, M.M. Fraga, S.K. De Oliveira, S.B. Sacchetti, S. Appenzeller, T. Robazzi, V.P. Ferriani, C.A. Len, C.A. Silva, C. Saad-Magalhaes
DOI: https://doi.org/10.55563/clinexprheumatol/yrb7m2
Letters to the Editor
CER17685
2025,43,2
Pg. 0387
Free to view
Cancer-associated myositis before and after the COVID-19 pandemic onset: a comment
H. Daungsupawong, V. Wiwanitkit
DOI: https://doi.org/10.55563/clinexprheumatol/mxdet4
H. Daungsupawong, V. Wiwanitkit
DOI: https://doi.org/10.55563/clinexprheumatol/mxdet4
CER17618
2025,43,2
Pg. 0388-0389
Free to view
Interleukin 16: a potential protective cytokine in idiopathic inflammatory myopathy
Y. Zhou, L. Kang, T. Liu, G. Yin, Q. Xie
DOI: https://doi.org/10.55563/clinexprheumatol/ma69i6
Y. Zhou, L. Kang, T. Liu, G. Yin, Q. Xie
DOI: https://doi.org/10.55563/clinexprheumatol/ma69i6
CER17797
2025,43,2
Pg. 0390
Free to view
Successful management of pulmonary hypertension with baricitinib in a dermatomyositis patient
C. Rizzo, F. Camarda, L. La Barbera, G. Guggino
DOI: https://doi.org/10.55563/clinexprheumatol/c6an8c
C. Rizzo, F. Camarda, L. La Barbera, G. Guggino
DOI: https://doi.org/10.55563/clinexprheumatol/c6an8c
CER18075
2025,43,2
Pg. 0391-0392
Free to view
Unravelling the link: anti-TIF1γ dermatomyositis associated with plexiform neurofibroma
J.A. Peñafiel-Sam, I. Aldecoa, J. Milisenda, J.A. Gómez-Puerta
DOI: https://doi.org/10.55563/clinexprheumatol/mmvy2o
J.A. Peñafiel-Sam, I. Aldecoa, J. Milisenda, J.A. Gómez-Puerta
DOI: https://doi.org/10.55563/clinexprheumatol/mmvy2o
CER18070
2025,43,2
Pg. 0393-0395
Free to view
Children with immune-mediated necrotising myopathy: a case series
Y. Yao, X.-L. He, F. Wang, G.-Q. Zhu, R.-X. Hu, G.-M. Li
DOI: https://doi.org/10.55563/clinexprheumatol/mk99se
Y. Yao, X.-L. He, F. Wang, G.-Q. Zhu, R.-X. Hu, G.-M. Li
DOI: https://doi.org/10.55563/clinexprheumatol/mk99se