Full Papers
Erosive arthropathy: clinical variance in lupus erythematosus and association with anti-CCP case series and review of the literature
J.B. Martinez, J.S. Valero, A.J. Bautista, J.F. Restrepo, E.L. Matteson, F. Rondon, A. Iglesias-Gamarra
CER2938
2007 Vol.25, N°1
PI 0047, PF 0053
Full Papers
Free to view
(click on article PDF icon to read the article)
PMID: 17417990 [PubMed]
Abstract
OBJECTIVES:
To describe the occurrence of erosive arthropathy in systemic lupus erythematosus (SLE) and its relationship to anti-CCP antibodies.
METHODS:
Retrospective medical record review of a case series of five female patients with SLE and erosive arthropathies.
RESULTS:
The initial disease presentation in all patients was a polyarthritis. Anti-CCP antibodies were detected in 4 out of 5 (80%) patients, 2 of whom had a positive rheumatoid factor.
CONCLUSIONS:
Erosive arthritis was strongly associated with the presence of anti-CCP antibodies in these patients with SLE, who presented with polyarthritis. Anti-CCP in patients with SLE may be a marker of a more severe joint disease.
