2025 Vol.43, N°12 - Table of contents
December - Sjögren’s disease 2025
One year in review
CER19305
2025,43,12
Pg. 2007-2019
Free to view
Clinical manifestations, imaging and treatment of Sjögren's disease: one year in review 2025
L.G. Chatzis, V. Manfrè, A. Colangelo, K. Delli, S. Arends, A.G. Tzioufas, H. Bootsma, L. Quartuccio, E. Bartoloni
DOI: https://doi.org/10.55563/clinexprheumatol/pjs5h9
L.G. Chatzis, V. Manfrè, A. Colangelo, K. Delli, S. Arends, A.G. Tzioufas, H. Bootsma, L. Quartuccio, E. Bartoloni
DOI: https://doi.org/10.55563/clinexprheumatol/pjs5h9
CER19490
2025,43,12
Pg. 2020-2028
Free to view
Evolving mechanisms in the pathogenesis of Sjögren’s disease: one year in review 2025
L.G. Chatzis, E. Pontarini, G. Fulvio, G. La Rocca, M. Bombardieri, C. Baldini
DOI: https://doi.org/10.55563/clinexprheumatol/2jlggn
L.G. Chatzis, E. Pontarini, G. Fulvio, G. La Rocca, M. Bombardieri, C. Baldini
DOI: https://doi.org/10.55563/clinexprheumatol/2jlggn
Environmental Rheumatology
CER19257
2025,43,12
Pg. 2029-2035
Free to view
Research evidence and patient perspective on the impact of lifestyle factors in patients with Sjögren’s disease
S. Arends, C. Bouillot
DOI: https://doi.org/10.55563/clinexprheumatol/ueexnj
S. Arends, C. Bouillot
DOI: https://doi.org/10.55563/clinexprheumatol/ueexnj
CER18997
2025,43,12
Pg. 2036-2044
Free to view
Clinical and serological differences of an Italian Sjögren’s disease cohort according to three geographic macro-area localisations
F. Atzeni, M.L. Currò, R. Dal Pozzolo, G. Cafaro, V. Manfrè, L. Quartuccio, F. Carubbi, A. Alunno, N. Del Papa, P. Cipriani, O. Berardicurti, R. Priori, A. Gattamelata, S. Guiducci, E. Bartoloni
on behalf of the Italian Research Group on Sjögren’s syndrome
DOI: https://doi.org/10.55563/clinexprheumatol/is2acv
F. Atzeni, M.L. Currò, R. Dal Pozzolo, G. Cafaro, V. Manfrè, L. Quartuccio, F. Carubbi, A. Alunno, N. Del Papa, P. Cipriani, O. Berardicurti, R. Priori, A. Gattamelata, S. Guiducci, E. Bartoloni
on behalf of the Italian Research Group on Sjögren’s syndrome
DOI: https://doi.org/10.55563/clinexprheumatol/is2acv
Full Papers
CER18553
2025,43,12
Pg. 2045-2052
Free to view
Association of visceral adipose tissue with inflammation and functional impairment in women with Sjögren's disease
A.S. Franco, I.H. Murai, T.H. Yang, V.L. Bonoldi, V. De Falco Caparbo, L. Guedes, D.S. Domiciano, S.G. Pasoto, C.P. Figueiredo, R.M. Pereira
DOI: https://doi.org/10.55563/clinexprheumatol/fa4tn3
A.S. Franco, I.H. Murai, T.H. Yang, V.L. Bonoldi, V. De Falco Caparbo, L. Guedes, D.S. Domiciano, S.G. Pasoto, C.P. Figueiredo, R.M. Pereira
DOI: https://doi.org/10.55563/clinexprheumatol/fa4tn3
CER18872
2025,43,12
Pg. 2053-2059
Free to view
Salivary cystatin D is a candidate non-invasive biomarker for primary Sjögren’s syndrome diagnosis and salivary gland injury
J. Wang, L. Mo, X. Tang, X. Feng, X. Liu, F. Li, Y. Huang, Y. Pan, J. Sun, H. Li, Y. Li
DOI: https://doi.org/10.55563/clinexprheumatol/mxfa55
J. Wang, L. Mo, X. Tang, X. Feng, X. Liu, F. Li, Y. Huang, Y. Pan, J. Sun, H. Li, Y. Li
DOI: https://doi.org/10.55563/clinexprheumatol/mxfa55
CER18762
2025,43,12
Pg. 2060-2068
Free to view
Comparison and clinical analysis of tissue-specific autoantibody levels in primary Sjögren's disease and other connective tissue diseases
Z.M. Wang, Y.S. Yang, X. Qi, Y. Zhang, X.P. Wang, J.L. Li, Z.Z. Huang, H.F. Guo, L.X. Gao
DOI: https://doi.org/10.55563/clinexprheumatol/tt1e0x
Z.M. Wang, Y.S. Yang, X. Qi, Y. Zhang, X.P. Wang, J.L. Li, Z.Z. Huang, H.F. Guo, L.X. Gao
DOI: https://doi.org/10.55563/clinexprheumatol/tt1e0x
CER18751
2025,43,12
Pg. 2069-2081
Free to view
Dysregulated plasmacytoid dendritic cells in primary Sjögren's syndrome: normal functionality but decreased quantities
R. Li, Y. Jia, X. Wu, M. Wang, C. Deng, Y. Peng, L. Zhao, W. Zhang, J. Zhou, M. Li, Y. Zhao, X. Zeng, Y. Fei
DOI: https://doi.org/10.55563/clinexprheumatol/ric794
R. Li, Y. Jia, X. Wu, M. Wang, C. Deng, Y. Peng, L. Zhao, W. Zhang, J. Zhou, M. Li, Y. Zhao, X. Zeng, Y. Fei
DOI: https://doi.org/10.55563/clinexprheumatol/ric794
CER19020
2025,43,12
Pg. 2082-2088
Free to view
Obesity in primary Sjögren’s disease
I. Cruz-Bautista, D. Gómez-Velasco, A. García-Torralba, C.A. Aguilar-Salinas, G. Hernandez-Molina
DOI: https://doi.org/10.55563/clinexprheumatol/9d0mr2
I. Cruz-Bautista, D. Gómez-Velasco, A. García-Torralba, C.A. Aguilar-Salinas, G. Hernandez-Molina
DOI: https://doi.org/10.55563/clinexprheumatol/9d0mr2
CER18757
2025,43,12
Pg. 2089-2101
Free to view
Quality of life in patients with Sjögren’s disease: a bibliometric analysis
W. Liu, Z. Guo, X. Wang, N. Lu, X. Tang, Q. Jiang, X. Zhou
DOI: https://doi.org/10.55563/clinexprheumatol/ujdncl
W. Liu, Z. Guo, X. Wang, N. Lu, X. Tang, Q. Jiang, X. Zhou
DOI: https://doi.org/10.55563/clinexprheumatol/ujdncl
CER18861
2025,43,12
Pg. 2102-2110
Free to view
Estimating the reliability of salivary gland ultrasound scoring in Sjögren’s disease: the outcome of an international training workshop
M.A. Suludere, N.R. Sluijpers, S. Arends, A.J. Stel, S. Jousse-Joulin, A. Hočevar, H. Bootsma, A. Vissink, K. Delli
Collaborator/s: A. Thatayatikom, A. Baer, A. Dumusc, A.C.F. Motta, A.S. Franco, A. Marino, C. Baldini, E. Maeland, F.R. De Oliveira, G. La Rocca, G. Fulvio, H. Munk, J. Gales, J. He, J. Van Santen, K.-A. Lee, M. Jonsson, M.L. Lemos Lopes, M. Tomiita, P. Olsson, S. Pringle, S. Cha, S. Liefers, V. Risso, V.F.M. Trevisani, Y. Jin, Y. Inoue
International Training Workshop
DOI: https://doi.org/10.55563/clinexprheumatol/derjeb
M.A. Suludere, N.R. Sluijpers, S. Arends, A.J. Stel, S. Jousse-Joulin, A. Hočevar, H. Bootsma, A. Vissink, K. Delli
Collaborator/s: A. Thatayatikom, A. Baer, A. Dumusc, A.C.F. Motta, A.S. Franco, A. Marino, C. Baldini, E. Maeland, F.R. De Oliveira, G. La Rocca, G. Fulvio, H. Munk, J. Gales, J. He, J. Van Santen, K.-A. Lee, M. Jonsson, M.L. Lemos Lopes, M. Tomiita, P. Olsson, S. Pringle, S. Cha, S. Liefers, V. Risso, V.F.M. Trevisani, Y. Jin, Y. Inoue
International Training Workshop
DOI: https://doi.org/10.55563/clinexprheumatol/derjeb
CER18987
2025,43,12
Pg. 2111-2123
Free to view
Uncovering CD248, MMP28, and SLC16A10 in Sjögren’s disease: a machine learning-driven SHAP approach for CD4+ T cell-associated biomarker discovery
Q. Wang, L. He, Y. Han
DOI: https://doi.org/10.55563/clinexprheumatol/2ffdc4
Q. Wang, L. He, Y. Han
DOI: https://doi.org/10.55563/clinexprheumatol/2ffdc4
CER19323
2025,43,12
Pg. 2124-2132
Free to view
Immunological signatures in patients with Sjögren's disease: association with systemic disease activity at diagnosis
L. Delgado, A. Flores-Chávez, A. Szántó, R. Priori, H. Bootsma, B. Armagan, L. Quartuccio, S. Praprotnik, Y. Suzuki, G. Hernandez-Molina, V.C. Romão, A. Sebastian, E. Bartoloni, M. Rischmueller, R. Solans, S.G. Pasoto, C. Fugmann, I. Sánchez Berná, F. Carubbi, V. Fernandes Moça Trevisani, V. Valim, S. Melchor, B. Maure Noia, E. Fonseca-Aizpuru, H. Nakamura, M. López-Dupla, M. Vazquez, M. Akasbi, G. Policarpo Torres, B. De Miguel Campo, M.R. Suru, C. Vericat Queralt, I.F. Horváth, I. Fischetti, A. Vissink, L. Kilic, V. Manfrè, K. Perdan Pirkmajer, Y. Fujisawa, M. Bandeira, K. Proc, R. Gerli, C. Kirana, N. Nardi, M. Ramos-Casals, P. Brito-Zerón
on behalf of the Sjögren Big Data Consortium
DOI: https://doi.org/10.55563/clinexprheumatol/zx7cp9
L. Delgado, A. Flores-Chávez, A. Szántó, R. Priori, H. Bootsma, B. Armagan, L. Quartuccio, S. Praprotnik, Y. Suzuki, G. Hernandez-Molina, V.C. Romão, A. Sebastian, E. Bartoloni, M. Rischmueller, R. Solans, S.G. Pasoto, C. Fugmann, I. Sánchez Berná, F. Carubbi, V. Fernandes Moça Trevisani, V. Valim, S. Melchor, B. Maure Noia, E. Fonseca-Aizpuru, H. Nakamura, M. López-Dupla, M. Vazquez, M. Akasbi, G. Policarpo Torres, B. De Miguel Campo, M.R. Suru, C. Vericat Queralt, I.F. Horváth, I. Fischetti, A. Vissink, L. Kilic, V. Manfrè, K. Perdan Pirkmajer, Y. Fujisawa, M. Bandeira, K. Proc, R. Gerli, C. Kirana, N. Nardi, M. Ramos-Casals, P. Brito-Zerón
on behalf of the Sjögren Big Data Consortium
DOI: https://doi.org/10.55563/clinexprheumatol/zx7cp9
CER19325
2025,43,12
Pg. 2133-2141
Free to view
Sex disparities in the phenotype at diagnosis of Sjögren's disease: artificial intelligence-driven characterisation in 17,416 patients
P. Brito-Zerón, A. Flores-Chávez, I.F. Horváth, R. Priori, H. Bootsma, B. Armagan, L. Quartuccio, S. Praprotnik, Y. Suzuki, G. Hernandez-Molina, V.C. Romão, A. Sebastian, E. Bartoloni, M. Rischmueller, R. Solans, S.G. Pasoto, G. Nordmark, I. Sánchez Berná, F. Carubbi, V. Fernandes Moça Trevisani, V. Valim, S. Melchor, B. Maure Noia, E. Fonseca-Aizpuru, L. Delgado, H. Nakamura, M. López-Dupla, M. Vazquez, M. Akasbi, G. Policarpo Torres, B. De Miguel Campo, R. Rouco, A. Szántó, A. Gattamelata, A. Vissink, L. Kilic, V. Manfrè, K. Perdan Pirkmajer, Y. Fujisawa, R. Pereira Da Costa, P. Wiland, R. Gerli, C. Kirana, N. Nardi, M. Ramos-Casals
on behalf of the Sjögren Big Data Consortium
DOI: https://doi.org/10.55563/clinexprheumatol/m8cq3f
P. Brito-Zerón, A. Flores-Chávez, I.F. Horváth, R. Priori, H. Bootsma, B. Armagan, L. Quartuccio, S. Praprotnik, Y. Suzuki, G. Hernandez-Molina, V.C. Romão, A. Sebastian, E. Bartoloni, M. Rischmueller, R. Solans, S.G. Pasoto, G. Nordmark, I. Sánchez Berná, F. Carubbi, V. Fernandes Moça Trevisani, V. Valim, S. Melchor, B. Maure Noia, E. Fonseca-Aizpuru, L. Delgado, H. Nakamura, M. López-Dupla, M. Vazquez, M. Akasbi, G. Policarpo Torres, B. De Miguel Campo, R. Rouco, A. Szántó, A. Gattamelata, A. Vissink, L. Kilic, V. Manfrè, K. Perdan Pirkmajer, Y. Fujisawa, R. Pereira Da Costa, P. Wiland, R. Gerli, C. Kirana, N. Nardi, M. Ramos-Casals
on behalf of the Sjögren Big Data Consortium
DOI: https://doi.org/10.55563/clinexprheumatol/m8cq3f
CER19158
2025,43,12
Pg. 2142-2151
Free to view
Two-dimentional shear wave elastography as an alternative method of ultrasound for major salivary gland evaluation in Sjögren’s disease
M.L. Lemos Lopes, V. Fernandes Moça Trevisani, D.U. Cantali, R. Coradin, L. Marinho Gonçalves, M. Lopes De Castro, G. Carra Forte, M.F. Peruci Felippe, B. Hochhegger
DOI: https://doi.org/10.55563/clinexprheumatol/2mako7
M.L. Lemos Lopes, V. Fernandes Moça Trevisani, D.U. Cantali, R. Coradin, L. Marinho Gonçalves, M. Lopes De Castro, G. Carra Forte, M.F. Peruci Felippe, B. Hochhegger
DOI: https://doi.org/10.55563/clinexprheumatol/2mako7
CER18977
2025,43,12
Pg. 2152-2160
Free to view
Diagnostic potential of soluble and membrane-bound inducible T-cell co-stimulator in Sjögren’s disease
N. Štucin, K. Perdan Pirkmajer, A. Hočevar, S. Čučnik, P. Žigon
DOI: https://doi.org/10.55563/clinexprheumatol/je5ba0
N. Štucin, K. Perdan Pirkmajer, A. Hočevar, S. Čučnik, P. Žigon
DOI: https://doi.org/10.55563/clinexprheumatol/je5ba0
CER19235
2025,43,12
Pg. 2161-2171
Free to view
An accurate predictive model for depressive symptoms in patients with primary Sjögren’s disease based on machine learning algorithms
L. Yang, Y. Tong, Y. Jin, X. Wang, Y. Yan, W. Lu, D. Su, J. Zou, K. Huang
DOI: https://doi.org/10.55563/clinexprheumatol/ar9d4k
L. Yang, Y. Tong, Y. Jin, X. Wang, Y. Yan, W. Lu, D. Su, J. Zou, K. Huang
DOI: https://doi.org/10.55563/clinexprheumatol/ar9d4k
CER19234
2025,43,12
Pg. 2172-2187
Free to view
Machine learning-based identification of pyroptosis-related genes as biomarkers and targets in primary Sjögren's syndrome
X. Jiang, X. Liang, Y. Hong, C. Hua, S. Gao, T. Zhang
DOI: https://doi.org/10.55563/clinexprheumatol/zpd69e
X. Jiang, X. Liang, Y. Hong, C. Hua, S. Gao, T. Zhang
DOI: https://doi.org/10.55563/clinexprheumatol/zpd69e
CER19139
2025,43,12
Pg. 2188-2196
Free to view
Length-based adequacy thresholds for submandibular gland core needle biopsy in suspected Sjögren’s disease: two-phase study
C.-F. Cheng, T.-C. Chen, M.-S. Hsieh, T.-Y. Lan, C.-Y. Huang, J.-H. Kao, Y.-H. Lin, C. Wang, H.-N. Huang, L.-W. Lin, Y.-J. Chiang, M.-F. Cheng, H.-S. Chu, Y.-M. Huang, C.-H. Lu, K.-J. Li, C.-Y. Shen, S.-C. Hsieh
DOI: https://doi.org/10.55563/clinexprheumatol/0nn5rk
C.-F. Cheng, T.-C. Chen, M.-S. Hsieh, T.-Y. Lan, C.-Y. Huang, J.-H. Kao, Y.-H. Lin, C. Wang, H.-N. Huang, L.-W. Lin, Y.-J. Chiang, M.-F. Cheng, H.-S. Chu, Y.-M. Huang, C.-H. Lu, K.-J. Li, C.-Y. Shen, S.-C. Hsieh
DOI: https://doi.org/10.55563/clinexprheumatol/0nn5rk
CER19429
2025,43,12
Pg. 2197-2201
Free to view
Treatment and follow-up of patients with Sjögren's disease associated interstitial lung disease: a case series
P.K. Panagopoulos, L.G. Chatzis, K. Malagari, A.V. Goules, A.G. Tzioufas
DOI: https://doi.org/10.55563/clinexprheumatol/k9tqpm
P.K. Panagopoulos, L.G. Chatzis, K. Malagari, A.V. Goules, A.G. Tzioufas
DOI: https://doi.org/10.55563/clinexprheumatol/k9tqpm
CER19444
2025,43,12
Pg. 2202-2208
Free to view
Correlation between colour Doppler activity and parenchymal alterations in salivary glands of patients with primary Sjögren’s disease
A. Zabotti, V. Manfrè, A. Nano, I. Giovannini, C. Fabro, L. Quartuccio
DOI: https://doi.org/10.55563/clinexprheumatol/slmkca
A. Zabotti, V. Manfrè, A. Nano, I. Giovannini, C. Fabro, L. Quartuccio
DOI: https://doi.org/10.55563/clinexprheumatol/slmkca
CER19492
2025,43,12
Pg. 2209-2216
Free to view
Clinical impact of anti-SSA antigenic specificity on disease activity and patient-reported outcomes in primary Sjögren’s disease: a real-life cohort study
S. Fonzetti, G. La Rocca, G. Fulvio, B. Dei, C. Porciani, F. Ferro, P. Migliorini, M. Mosca, C. Baldini
DOI: https://doi.org/10.55563/clinexprheumatol/t01mio
S. Fonzetti, G. La Rocca, G. Fulvio, B. Dei, C. Porciani, F. Ferro, P. Migliorini, M. Mosca, C. Baldini
DOI: https://doi.org/10.55563/clinexprheumatol/t01mio
Review
CER19491
2025,43,12
Pg. 2217-2223
Free to view
Damage accrual in Sjögren’s disease. Prevalence, risk factors and impact on quality of life: a systematic review
B. Dei, G. La Rocca, R. Dal Pozzolo, G. Fulvio, E. Bartoloni, C. Baldini
DOI: https://doi.org/10.55563/clinexprheumatol/c80y4h
B. Dei, G. La Rocca, R. Dal Pozzolo, G. Fulvio, E. Bartoloni, C. Baldini
DOI: https://doi.org/10.55563/clinexprheumatol/c80y4h
Letters to the Editor
CER18472
2025,43,12
Pg. 2224
Free to view
Comment on: Beyond diagnosis: exploring the significance of IgG4+ plasma cell count through immunostaining in IgG4-related disease
M.-W. Chiang, P.-C. Wu
DOI: https://doi.org/10.55563/clinexprheumatol/fr0v5l
M.-W. Chiang, P.-C. Wu
DOI: https://doi.org/10.55563/clinexprheumatol/fr0v5l
CER18578
2025,43,12
Pg. 2225
Free to view
Reply to the comment on: Beyond diagnosis: exploring the significance of IgG4+ plasma cell count through immunostaining in IgG4-related disease
E. Martín-Nares, G. Hernández-Molina
DOI: https://doi.org/10.55563/clinexprheumatol/0mrihy
E. Martín-Nares, G. Hernández-Molina
DOI: https://doi.org/10.55563/clinexprheumatol/0mrihy
CER19272
2025,43,12
Pg. 2226-2228
Free to view
Mechanism-driven innovative drug development for primary Sjögren's disease: insights from global clinical trial landscapes
F. Wu, L.W. Dai, G. Wu
DOI: https://doi.org/10.55563/clinexprheumatol/i0vmup
F. Wu, L.W. Dai, G. Wu
DOI: https://doi.org/10.55563/clinexprheumatol/i0vmup
CER19415
2025,43,12
Pg. 2229-2230
Free to view
Successful treatment of a rare case of coronary vasculitis associated with diffuse large B-cell lymphoma in a patient affected by Sjögren’s disease
V. Manfrè, A. Nano, M.T. Rizzo, S. Longhino, L. Quartuccio
DOI: https://doi.org/10.55563/clinexprheumatol/y64r2c
V. Manfrè, A. Nano, M.T. Rizzo, S. Longhino, L. Quartuccio
DOI: https://doi.org/10.55563/clinexprheumatol/y64r2c